HitPredict

Interactor 1: RRAS2 (P62070)
Ras-related protein R-Ras2 (EC 3.6.5.-) (Ras-like protein TC21) (Teratocarcinoma oncogene)
Gene: RRAS2

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 204 Hs			1 192
+	Hs
		918847 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564470 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		925294 RAB35_HUMAN (10-200): 4.12e-84: 249: 27.50		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564468 RRAS2_HUMAN (1-204): 2.76e-84: 249: 100.00		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545307 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		545304 RRAS2_HUMAN (1-204): 2.76e-84: 249: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		545392 RAB35_HUMAN (10-200): 4.12e-84: 249: 27.50		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		918948 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		1070394 RAB35_HUMAN (10-200): 4.12e-84: 249: 27.50		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892305 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		918849 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		892303 RRAS2_HUMAN (1-204): 2.76e-84: 249: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		892386 RAB35_HUMAN (10-200): 4.12e-84: 249: 27.50		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		893872 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		894031 RAB35_HUMAN (10-200): 4.12e-84: 249: 27.50		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900355 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		900494 RAB35_HUMAN (10-200): 4.12e-84: 249: 27.50		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Zm
		73944 B4FAE1_MAIZE (8-202): 3.3e-85: 251: 28.22		B4FAE1_MAIZE (4-190): 3.17e-75: 226: 25.53
+	Hs
		436244 RAB1A_HUMAN (1-202): 8.67e-85: 251: 26.32		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		436241 RRAS2_HUMAN (1-204): 2.76e-84: 249: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45