Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: SH3R2 (Q8TEC5)
E3 ubiquitin-protein ligase SH3RF2 (EC 2.3.2.27) (Heart protein phosphatase 1-binding protein) (HEPP1) (POSH-eliminating RING protein) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (RING-type E3 ubiquitin transferase SH3RF2) (SH3 domain-containing RING finger protein 2)
Gene: SH3RF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.680

The method score is based on:

Property Details
Experiments 22321011, 19945436, 19389623
Identification Methods two hybrid, affinity chromatography technology, far western blotting, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008157 - protein phosphatase 1 binding
GO:0046872 - metal ion binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 330
Hs

1 729
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024