HitPredict

Interactor 1: PRS4 (P62191)
26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene: PSMC1

Interactor 2: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 36652389
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 128
+	At
		1092307 PS10A_ARATH (56-431): 5.64e-161: 461: 42.02		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		913240 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Hs
		906983 PRS8_HUMAN (55-433): 1.06e-123: 366: 46.70		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	At
		1092257 PS10B_ARATH (66-435): 1.2e-138: 404: 41.89		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1092354 PRS4B_ARATH (1-440): 3.49e-136: 399: 76.75		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1092413 PRS4A_ARATH (1-440): 1.58e-135: 398: 76.30		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		913239 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	At
		1092308 PRS6B_ARATH (51-431): 9.28e-128: 377: 48.03		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		906982 PRS8_HUMAN (55-433): 1.06e-123: 366: 46.70		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	At
		1091926 PRS8B_ARATH (25-433): 9.94e-126: 372: 46.59		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1091962 PRS8A_ARATH (54-433): 2.4e-124: 369: 46.98		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		474950 PRS6B_HUMAN (50-433): 1.06e-122: 364: 48.96		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00
+	At
		1092378 PRS7A_ARATH (35-440): 4.3e-122: 363: 39.34		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Dm
		547940 Q9V3V6_DROME (73-431): 3.12e-111: 335: 46.70		RS27A_DROME (1-77): 3.98e-38: 127: 98.70
+	At
		1092294 CD48D_ARATH (171-418): 1.18e-81: 269: 43.15		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59