HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: Q58EY0 (Q58EY0)
RAR related orphan receptor B isoform 1 (RAR-related orphan receptor B) (cDNA, FLJ93970, Homo sapiens RAR-related orphan receptor B (RORB), mRNA)
Gene: RORB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15604093, 32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 459
+	Hs
		907112 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RORB_HUMAN (2-459): 7.27e-137: 403: 99.78
+	Hs
		798685 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		Q58EY0_HUMAN (1-459): 1.48e-138: 407: 100.00
+	Hs
		723175 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RORA_HUMAN (2-453): 2.48e-115: 350: 61.15
+	Hs
		846406 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RORG_HUMAN (2-454): 9.76e-106: 325: 46.25
+	Hs
		823807 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		823806 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		798611 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		509930 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		VDR_HUMAN (3-453): 6.64e-82: 261: 21.44
+	Hs
		730213 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		265859 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		NR1I2_HUMAN (8-452): 8.17e-81: 258: 22.72
+	Hs
		500362 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARB_HUMAN (9-138): 6.04e-46: 167: 42.31
+	Hs
		530791 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARG_HUMAN (9-84): 1.22e-44: 163: 63.16
+	Hs
		487934 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARA_HUMAN (9-84): 3.92e-43: 159: 61.84
+	Hs
		740491 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		PPARG_HUMAN (8-128): 1.04e-45: 167: 46.34
+	Hs
		587150 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RXRA_HUMAN (10-91): 4.41e-28: 117: 57.32
+	Hs
		906997 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		PPARD_HUMAN (244-450): 1.28e-15: 80.5: 26.07
+	Hs
		823822 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75