HitPredict

Interactor 1: PRS8 (P62198)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: Psmc5

Interactor 2: RD23B (Q4KMA2)
UV excision repair protein RAD23 homolog B
Gene: Rad23b

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20178748
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Rn			1 415
+	Hs
		872249 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51
+	Rn
		906973 PRS4_RAT (4-396): 7.85e-130: 382: 46.31		RD23B_RAT (1-415): 3.84e-120: 357: 100.00
+	Hs
		872248 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51
+	Hs
		872134 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RD23A_HUMAN (1-415): 2.25e-93: 287: 54.46
+	At
		1352317 PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62		DSK2A_ARATH (1-413): 7.19e-64: 215: 14.88
+	Hs
		872133 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		RD23A_HUMAN (1-415): 2.25e-93: 287: 54.46
+	Hs
		907185 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		UBQL1_HUMAN (1-410): 4.05e-64: 217: 13.60
+	Dm
		820528 PRS4_DROME (4-396): 3.02e-138: 403: 45.04		Q9VWD9_DROME (1-363): 1.21e-59: 204: 13.70
+	Hs
		906946 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		UBQL1_HUMAN (1-410): 4.05e-64: 217: 13.60
+	Mm
		907218 PRS8_MOUSE (1-406): 1.42e-136: 398: 100.00		UBQL2_MOUSE (1-363): 8.06e-54: 190: 14.26
+	Hs
		907182 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Hs
		906941 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Hs
		907171 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		UBQL4_HUMAN (1-363): 9.84e-41: 154: 14.29
+	Hs
		906983 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RL40_HUMAN (1-112): 6.75e-40: 140: 24.11
+	Hs
		906929 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		UBQL4_HUMAN (1-363): 9.84e-41: 154: 14.29
+	Mm
		476745 PRS8_MOUSE (1-406): 1.42e-136: 398: 100.00		UBC_MOUSE (1-110): 8.25e-31: 126: 23.64
+	Hs
		906808 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		RL40_HUMAN (1-112): 6.75e-40: 140: 24.11
+	Mm
		476744 PRS4_MOUSE (4-396): 7.85e-130: 382: 46.31		UBC_MOUSE (1-110): 8.25e-31: 126: 23.64
+	Dm
		820508 PRS4_DROME (4-396): 3.02e-138: 403: 45.04		Q9VCD5_DROME (1-207): 8.28e-16: 79.1: 16.67
+	Hs
		906982 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RS27A_HUMAN (1-91): 4.3e-16: 76.9: 26.37