HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 487
+	Hs
		682160 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		AKT2_HUMAN (3-353): 1.95e-134: 398: 21.88
+	Dm
		715095 UBE2N_DROME (5-152): 6.43e-62: 190: 34.21		AKT1_DROME (1-344): 1.74e-134: 403: 22.32
+	Hs
		647861 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		MARK3_HUMAN (29-451): 4.09e-123: 378: 21.32
+	Hs
		908733 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		MARK2_HUMAN (6-486): 9.18e-123: 378: 20.68
+	Hs
		131560 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		STK25_HUMAN (14-327): 8.86e-120: 359: 48.74
+	Hs
		568615 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90
+	Hs
		829083 UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46		TNIK_HUMAN (8-309): 2.1e-73: 254: 44.80