HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 513
+	Hs
		895800 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		SMU1_HUMAN (1-513): 7.53e-153: 447: 100.00
+	Hs
		909129 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45
+	Hs
		903084 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		245581 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		TBL1X_HUMAN (252-512): 3.08e-62: 215: 18.38
+	Hs
		849435 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		TBL1R_HUMAN (252-512): 4.37e-62: 213: 16.96
+	Hs
		245625 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		TBL1X_HUMAN (252-512): 3.08e-62: 215: 18.38
+	Hs
		1282344 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		TBL1R_HUMAN (252-512): 4.37e-62: 213: 16.96
+	Hs
		921784 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		919704 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		849304 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		895772 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		908940 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		908310 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		908333 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		908449 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		TBL3_HUMAN (213-376): 4.84e-09: 60.8: 24.55