Protein: RXFP1
Relaxin receptor 1 (Leucine-rich repeat-containing G-protein coupled receptor 7) (Relaxin family peptide receptor 1)

Gene: RXFP1
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q9HBX9

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007567 - parturition
GO:0008528 - G protein-coupled peptide receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1237968

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

19

High-throughput

0.691

High

1271351

LRC8D
Volume-regulated anion channel subunit LRRC8D

1

20

High-throughput

0.691

High

1278324

LRP10
Low-density lipoprotein receptor-related protein 10

1

6

High-throughput

0.691

High

1358618

BT2A2
Butyrophilin subfamily 2 member A2

1

4

High-throughput

0.691

High

1438493

NOTC3
Neurogenic locus notch homolog protein 3

1

1

High-throughput

0.691

High

1438498

LRP12
Low-density lipoprotein receptor-related protein 12

1

6

High-throughput

0.691

High

1438486

RAB6B
Ras-related protein Rab-6B

1

3

High-throughput

0.618

High

1438496

TMX2
Thioredoxin-related transmembrane protein 2

1

1

High-throughput

0.618

High

1006728

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.579

High

605818

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

Small-scale

0.575

High

732710

ARRB2
Beta-arrestin-2

1

5

Small-scale

0.575

High

190639

MRP4
ATP-binding cassette sub-family C member 4

1

1

High-throughput

0.536

High

190690

MRP5
ATP-binding cassette sub-family C member 5

1

1

High-throughput

0.536

High

243829

ADCY3
Adenylate cyclase type 3

1

1

High-throughput

0.536

High

261280

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.536

High

320505

TM63A
Mechanosensitive cation channel TMEM63A

1

2

High-throughput

0.536

High

336578

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

420050

B3A2
Anion exchange protein 2

1

3

High-throughput

0.536

High

604218

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.536

High

661336

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

14

High-throughput

0.536

High

1023446

AT8B2
Phospholipid-transporting ATPase ID

1

5

High-throughput

0.536

High

1032662

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

7

High-throughput

0.536

High

1043238

TAP2
Antigen peptide transporter 2

1

2

High-throughput

0.536

High

1125874

FZD2
Frizzled-2

1

1

High-throughput

0.536

High

1212305

TM63B
Mechanosensitive cation channel TMEM63B

1

2

High-throughput

0.536

High

1212502

MRP7
ATP-binding cassette sub-family C member 10

1

2

High-throughput

0.536

High

1275410

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

2

High-throughput

0.536

High

1333118

AT11C
Phospholipid-transporting ATPase IG

1

3

High-throughput

0.536

High

1356279

ABHD3
Phospholipase ABHD3

1

1

High-throughput

0.536

High

1372396

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

11

High-throughput

0.536

High

1382887

TTC17
Tetratricopeptide repeat protein 17

1

1

High-throughput

0.536

High

1414835

ABHD6
Monoacylglycerol lipase ABHD6

1

1

High-throughput

0.536

High

1417153

S12A9
Solute carrier family 12 member 9

1

5

High-throughput

0.536

High

1438485

ST7
Suppressor of tumorigenicity 7 protein

1

5

High-throughput

0.536

High

1438487

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

3

High-throughput

0.536

High

1438492

S12A6
Solute carrier family 12 member 6

1

5

High-throughput

0.536

High

1438494

PCDGK
Protocadherin gamma-C3

1

1

High-throughput

0.536

High

1438495

S12A4
Solute carrier family 12 member 4

1

5

High-throughput

0.536

High

1438499

S12A7
Solute carrier family 12 member 7

1

4

High-throughput

0.536

High

1154826

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

1

0

High-throughput

0.513

High

1209928

PPM1L
Protein phosphatase 1L

1

0

High-throughput

0.513

High

1248256

KCNT2
Potassium channel subfamily T member 2

1

0

High-throughput

0.513

High

1335574

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.513

High

1356603

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

1400551

TM237
Transmembrane protein 237

1

0

High-throughput

0.513

High

1407396

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.513

High

1438491

NB5R1
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.513

High

72679

UPK3L
Uroplakin-3b-like protein 1

1

2

High-throughput

0.489

High

161156

ABCD4
Lysosomal cobalamin transporter ABCD4

1

4

High-throughput

0.489

High

699147

CALX
Calnexin

1

8

High-throughput

0.489

High

1050541

UBE3A
Ubiquitin-protein ligase E3A

1

4

High-throughput

0.489

High

1087080

FSTL1
Follistatin-related protein 1

1

4

High-throughput

0.489

High

1138983

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

4

High-throughput

0.489

High

1164171

CP51A
Lanosterol 14-alpha demethylase

1

1

High-throughput

0.489

High

1238375

RETST
All-trans-retinol 13,14-reductase

1

3

High-throughput

0.489

High

1322742

CNPY4
Protein canopy homolog 4

1

18

High-throughput

0.489

High

1337677

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.489

High

1351785

ST7L
Suppressor of tumorigenicity 7 protein-like

1

5

High-throughput

0.489

High

1352373

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.489

High

1353426

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

7

High-throughput

0.489

High

1364155

TM131
Transmembrane protein 131

1

1

High-throughput

0.489

High

1412986

CNPY3
Protein canopy homolog 3

1

18

High-throughput

0.489

High

1434876

PCX3
Pecanex-like protein 3

1

1

High-throughput

0.489

High

1436052

DJC18
DnaJ homolog subfamily C member 18

1

6

High-throughput

0.489

High

1438483

ABCB9
ABC-type oligopeptide transporter ABCB9

1

2

High-throughput

0.489

High

1438484

AT132
Polyamine-transporting ATPase 13A2

1

16

High-throughput

0.489

High

1438489

DNJB9
DnaJ homolog subfamily B member 9

1

3

High-throughput

0.489

High

1438497

DHRS7
Dehydrogenase/reductase SDR family member 7

1

3

High-throughput

0.489

High

1064393

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

3

Small-scale

0.484

High

665908

AKAP5
A-kinase anchor protein 5

1

0

Small-scale

0.458

High

953836

C1QT8
Complement C1q tumor necrosis factor-related protein 8

1

1

Small-scale

0.437

High

1220820

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

1211080

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

1

High-throughput

0.407

High

226454

SNG2
Synaptogyrin-2

1

0

High-throughput

0.279

Low

450273

HYEP
Epoxide hydrolase 1

1

0

High-throughput

0.279

Low

907846

CLCN7
H(+)/Cl(-) exchange transporter 7

1

0

High-throughput

0.279

Low

1085159

TMM94
Transmembrane protein 94

1

0

High-throughput

0.279

Low

1248670

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.279

Low

1324315

GHDC
GH3 domain-containing protein

1

0

High-throughput

0.279

Low

1385204

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1406322

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.279

Low

1410674

APOL2
Apolipoprotein L2

1

0

High-throughput

0.279

Low

1411073

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

1

0

High-throughput

0.279

Low

1414294

ABHEA
Protein ABHD14A

1

0

High-throughput

0.279

Low

1415729

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

High-throughput

0.279

Low

1438488

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

1438490

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

1325394

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.249

Low

1360547

REL3
Relaxin-3

1

0

Small-scale

0.213

Low


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Last updated: 11Aug2025