HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: GAPD1 (Q14C86)
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6)
Gene: GAPVD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1478
+	Hs
		909664 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DAB2P_HUMAN (62-602): 5.14e-111: 382: 16.72
+	Sp
		144985 RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77		IQG1_SCHPO (4-483): 1.47e-105: 371: 14.20
+	Hs
		910133 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NGAP_HUMAN (69-628): 8.13e-78: 283: 14.24
+	Hs
		909931 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SYGP1_HUMAN (72-507): 6.42e-73: 270: 15.00
+	Mm
		99940 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		SYGP1_MOUSE (72-447): 6.74e-73: 270: 15.26
+	Hs
		909774 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RASL3_HUMAN (94-635): 9.53e-71: 260: 16.72
+	Hs
		598455 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NF1_HUMAN (144-468): 2.57e-58: 225: 18.26
+	Hs
		108670 G9K388_HUMAN (1-239): 1.5e-165: 464: 99.58		RIN3_HUMAN (1208-1475): 5.18e-48: 189: 17.69
+	Mm
		910233 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NF1_MOUSE (144-468): 2.05e-57: 222: 17.98
+	Hs
		909924 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ANR27_HUMAN (1214-1472): 7.13e-56: 214: 20.15
+	Mm
		910298 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		VP9D1_MOUSE (1221-1475): 5.12e-44: 173: 15.94