HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: AAK1 (Q2M2I8)
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)
Gene: AAK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Hs			1 961
+	Hs
		909730 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK2_HUMAN (6-739): 5.77e-127: 405: 15.61
+	Xl
		223344 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q804T2_XENLA (2-704): 1.66e-125: 399: 15.33
+	Mm
		910234 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK2_MOUSE (6-739): 5.18e-123: 394: 15.63
+	Hs
		909810 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MINK1_HUMAN (23-889): 2.9e-117: 391: 15.13
+	Mm
		910231 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK3_MOUSE (2-692): 3.36e-120: 386: 15.60
+	Xl
		223345 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q8QGV3_XENLA (10-720): 1.54e-120: 388: 16.25
+	Hs
		647862 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK3_HUMAN (2-692): 2.26e-119: 383: 14.89
+	Hs
		910106 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK1_HUMAN (4-739): 6.05e-119: 383: 17.11
+	Hs
		159186 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CSKP_HUMAN (43-677): 4.25e-116: 379: 16.03
+	Mm
		910248 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		BRSK1_MOUSE (46-802): 4.42e-117: 378: 17.14
+	Mm
		910318 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK1_MOUSE (4-739): 1.17e-116: 378: 17.13
+	Hs
		681770 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AKT1_HUMAN (7-386): 1.25e-118: 373: 16.50
+	Mm
		910308 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK4_MOUSE (8-663): 1.63e-115: 373: 17.45
+	Hs
		909916 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK4_HUMAN (8-663): 4.45e-115: 372: 17.45
+	At
		965360 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CIPKC_ARATH (28-356): 3.58e-117: 369: 21.30
+	Hs
		229938 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NUAK1_HUMAN (43-478): 6.05e-102: 334: 23.21
+	Mm
		910266 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NUAK1_MOUSE (43-478): 3.06e-98: 324: 22.44
+	At
		965291 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CDPK1_ARATH (43-327): 3.22e-97: 320: 25.42
+	Hs
		909932 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NEK1_HUMAN (52-393): 2.34e-20: 99.4: 27.20
+	Hs
		909721 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NEK10_HUMAN (52-308): 6.75e-17: 88.2: 27.47