HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: CRTC1 (Q68ED7)
CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
Gene: CRTC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 630
+	Rn
		910356 1433E_RAT (1-255): 4.87e-154: 430: 100.00		CRTC1_RAT (1-630): 2.88e-70: 241: 96.83
+	Hs
		909700 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CRTC1_HUMAN (1-630): 1.01e-59: 212: 85.02
+	Hs
		909699 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CRTC3_HUMAN (2-630): 7.48e-38: 150: 32.69
+	Hs
		909630 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CRTC2_HUMAN (2-630): 5.13e-32: 133: 31.98
+	Hs
		909666 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		TENS2_HUMAN (164-546): 1.59e-25: 114: 15.56
+	Hs
		909712 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		OTOG_HUMAN (40-583): 5.63e-19: 94.1: 10.11
+	Hs
		297821 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		K0754_HUMAN (5-298): 3.84e-15: 81.8: 7.59
+	Hs
		257595 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ANR17_HUMAN (41-579): 3.77e-09: 62.1: 12.08