HitPredict

Interactor 1: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Interactor 2: HNRPF (P52597)
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]
Gene: HNRNPF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	9111328, 32960270
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~zf-RNPHF
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 415
+	Hs
		911574 NCBP2_HUMAN (1-156): 2.6e-49: 157: 100.00		PABP4_HUMAN (1-412): 9.44e-80: 260: 15.75
+	Hs
		550190 NCBP2_HUMAN (1-156): 2.6e-49: 157: 100.00		PABP1_HUMAN (1-410): 9.92e-79: 257: 13.66
+	Hs
		729194 NCBP2_HUMAN (1-156): 2.6e-49: 157: 100.00		HNRH1_HUMAN (1-413): 8.63e-70: 228: 74.82
+	Hs
		550262 PABP1_HUMAN (4-156): 1.18e-28: 111: 18.41		PABP4_HUMAN (1-412): 9.44e-80: 260: 15.75
+	Hs
		550097 PABP1_HUMAN (4-156): 1.18e-28: 111: 18.41		PABP1_HUMAN (1-410): 9.92e-79: 257: 13.66
+	Hs
		550311 PABP1_HUMAN (4-156): 1.18e-28: 111: 18.41		PAP1L_HUMAN (1-414): 7.31e-78: 254: 13.79
+	Hs
		550464 PABP1_HUMAN (4-156): 1.18e-28: 111: 18.41		PABP3_HUMAN (1-411): 3.56e-72: 239: 12.30
+	Hs
		1102095 PABP4_HUMAN (4-156): 4.7e-28: 110: 17.18		PABP3_HUMAN (1-411): 3.56e-72: 239: 12.30
+	Sc
		403685 NCBP2_YEAST (10-150): 3.49e-39: 133: 52.48		PABP_YEAST (11-294): 3.77e-42: 158: 11.68
+	Hs
		729013 NCBP2_HUMAN (1-156): 2.6e-49: 157: 100.00		HNRH3_HUMAN (13-86): 3.78e-11: 66: 39.19
+	Hs
		1087365 ELAV2_HUMAN (33-122): 3.46e-26: 103: 21.11		GRSF1_HUMAN (252-379): 4.88e-18: 87.9: 20.46
+	Hs
		506129 PABP4_HUMAN (4-156): 4.7e-28: 110: 17.18		PAB4L_HUMAN (9-91): 1.8e-12: 70.3: 15.48
+	Hs
		550114 PABP1_HUMAN (4-156): 1.18e-28: 111: 18.41		NUCL_HUMAN (75-370): 1.43e-11: 68.3: 19.21
+	Hs
		550250 PABP1_HUMAN (4-156): 1.18e-28: 111: 18.41		ELAV2_HUMAN (278-365): 3.01e-11: 66.4: 12.09
+	Hs
		1090216 PABP4_HUMAN (4-156): 4.7e-28: 110: 17.18		ELAV2_HUMAN (278-365): 3.01e-11: 66.4: 12.09
+	Hs
		506127 ELAV2_HUMAN (33-122): 3.46e-26: 103: 21.11		PAB4L_HUMAN (9-91): 1.8e-12: 70.3: 15.48
+	Xl
		1362166 ELAV2_XENLA (7-155): 4.29e-26: 103: 16.67		ELAV2_XENLA (258-365): 4.36e-11: 66.1: 10.71