Protein: NCBP2
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)

Gene: NCBP2, CBC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 200
UniProt ID: Q08920

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000243 - commitment complex
GO:0000339 - RNA cap binding
GO:0000398 - mRNA splicing, via spliceosome
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757550

NCBP1
Nuclear cap-binding protein complex subunit 1

20

8

Small-scale

0.988

High

743561

RU1A
U1 small nuclear ribonucleoprotein A

7

1

Small-scale

0.960

High

921614

NRD1
Protein NRD1

6

1

Small-scale

0.947

High

1025660

NAM8
Protein NAM8

6

15

Small-scale

0.943

High

1065111

YRA1
RNA annealing protein YRA1

6

18

Small-scale

0.931

High

1028000

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

5

20

Small-scale

0.922

High

1031070

NOP3
Serine/arginine

5

20

Small-scale

0.922

High

1047393

RSE1
Pre-mRNA-splicing factor RSE1

5

5

Small-scale

0.922

High

403685

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

5

19

Small-scale

0.915

High

1044067

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

6

0

Small-scale

0.894

High

625141

PRP9
Pre-mRNA-splicing factor PRP9

4

2

Small-scale

0.873

High

808780

NAB3
Nuclear polyadenylated RNA-binding protein 3

4

0

High-throughput

0.849

High

779937

YRA2
RNA annealing protein YRA2

4

0

High-throughput

0.836

High

826553

MSL1
U2 small nuclear ribonucleoprotein B''

3

20

Small-scale

0.827

High

1065106

RU2A
U2 small nuclear ribonucleoprotein A'

3

2

Small-scale

0.827

High

1065107

CWC2
Pre-mRNA-splicing factor CWC2

3

9

High-throughput

0.827

High

676779

GBP2
Serine/arginine

2

18

High-throughput

0.754

High

892795

SF3B1
U2 snRNP component HSH155

2

10

High-throughput

0.754

High

1037760

CUS1
Cold sensitive U2 snRNA suppressor 1

2

2

Small-scale

0.754

High

1059211

PRP11
Pre-mRNA-splicing factor PRP11

2

4

Small-scale

0.754

High

1065125

HSH49
Protein HSH49

2

18

High-throughput

0.754

High

1039063

IMA1
Importin subunit alpha

8

5

Small-scale

0.742

High

1065127

MEX67
mRNA export factor MEX67

7

3

Small-scale

0.736

High

1059551

LUC7
Protein LUC7

6

2

Small-scale

0.730

High

1053876

IMB1
Importin subunit beta-1

6

4

High-throughput

0.727

High

738936

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

6

1

Small-scale

0.723

High

1054390

SMD2
Small nuclear ribonucleoprotein Sm D2

5

2

High-throughput

0.714

High

919585

YG5B
Uncharacterized RNA-binding protein YGR250C

2

15

High-throughput

0.693

High

751802

PRP8
Pre-mRNA-splicing factor 8

4

3

High-throughput

0.686

High

817175

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

4

High-throughput

0.686

High

918231

SNU71
U1 small nuclear ribonucleoprotein component SNU71

5

0

Small-scale

0.684

High

750316

PRP40
Pre-mRNA-processing protein PRP40

4

4

Small-scale

0.676

High

813376

PRP39
Pre-mRNA-processing factor 39

4

16

Small-scale

0.676

High

1044043

PRP42
U1 small nuclear ribonucleoprotein component PRP42

4

20

Small-scale

0.676

High

815340

IF4F2
Eukaryotic initiation factor 4F subunit p130

6

14

Small-scale

0.668

High

444645

DED1
ATP-dependent RNA helicase DED1

3

12

Small-scale

0.664

High

1052785

RU1C
U1 small nuclear ribonucleoprotein C

4

0

Small-scale

0.648

High

594615

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

1

Small-scale

0.640

High

702288

YJU2
Splicing factor YJU2

3

1

High-throughput

0.640

High

739215

PRP19
Pre-mRNA-processing factor 19

3

8

High-throughput

0.640

High

744177

BRR2
Pre-mRNA-splicing helicase BRR2

3

14

High-throughput

0.640

High

780234

SN114
Pre-mRNA-splicing factor SNU114

3

8

High-throughput

0.640

High

829964

PRP17
Pre-mRNA-processing factor 17

3

5

High-throughput

0.640

High

847840

SMD3
Small nuclear ribonucleoprotein Sm D3

3

3

High-throughput

0.640

High

924765

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

3

1

High-throughput

0.640

High

1043512

CEF1
Pre-mRNA-splicing factor CEF1

3

3

High-throughput

0.640

High

1044026

CWC15
Pre-mRNA-splicing factor CWC15

3

1

High-throughput

0.640

High

1053564

SN309
Pre-mRNA-splicing factor SNT309

3

1

High-throughput

0.640

High

1065114

CLF1
Pre-mRNA-splicing factor CLF1

3

20

High-throughput

0.640

High

1065117

PRP46
Pre-mRNA-splicing factor PRP46

3

8

High-throughput

0.640

High

815264

IF4F1
Eukaryotic initiation factor 4F subunit p150

4

11

Small-scale

0.621

High

518151

SSBP1
Single-stranded nucleic acid-binding protein

1

18

High-throughput

0.618

High

657009

BUR1
Serine/threonine-protein kinase BUR1

1

7

Small-scale

0.618

High

671459

RNA15
mRNA 3'-end-processing protein RNA15

1

19

High-throughput

0.618

High

676990

SRO9
RNA-binding protein SRO9

1

20

High-throughput

0.618

High

692641

NSR1
Nuclear localization sequence-binding protein

1

20

High-throughput

0.618

High

751993

LHP1
La protein homolog

1

20

High-throughput

0.618

High

807698

HRB1
Serine/arginine

1

15

High-throughput

0.618

High

863101

CWC26
Pre-mRNA-splicing factor CWC26

1

1

High-throughput

0.618

High

922181

PAP2
Poly(A) RNA polymerase protein 2

1

2

High-throughput

0.618

High

1044570

CTK1
CTD kinase subunit alpha

1

5

Small-scale

0.618

High

1053616

MRD1
Multiple RNA-binding domain-containing protein 1

1

15

High-throughput

0.618

High

1065105

NCBP2
Nuclear cap-binding protein subunit 2

1

17

High-throughput

0.618

High

150193

THP2
THO complex subunit THP2

3

0

Small-scale

0.613

High

605934

HPR1
THO complex subunit HPR1

3

0

Small-scale

0.613

High

1042538

CWC21
Pre-mRNA-splicing factor CWC21

3

0

High-throughput

0.613

High

454014

IF4E
Eukaryotic translation initiation factor 4E

2

1

Small-scale

0.584

High

625054

PRP6
Pre-mRNA-splicing factor 6

2

15

High-throughput

0.584

High

638089

ISY1
Pre-mRNA-splicing factor ISY1

2

2

High-throughput

0.584

High

664625

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

7

High-throughput

0.584

High

739282

PRP21
Pre-mRNA-splicing factor PRP21

2

2

Small-scale

0.584

High

780866

MUD2
Splicing factor MUD2

2

1

High-throughput

0.584

High

796470

SLT11
Pre-mRNA-splicing factor SLT11

2

2

High-throughput

0.584

High

919447

PBP1
PAB1-binding protein 1

2

10

High-throughput

0.584

High

921201

THO2
THO complex subunit 2

2

4

Small-scale

0.584

High

1025198

SEN1
Helicase SEN1

2

13

High-throughput

0.584

High

1030598

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

6

High-throughput

0.584

High

1044950

SYF1
Pre-mRNA-splicing factor SYF1

2

20

High-throughput

0.584

High

734488

BTAF1
TATA-binding protein-associated factor MOT1

1

13

Small-scale

0.561

High

753271

MFT1
THO complex subunit MFT1

2

0

Small-scale

0.559

High

923940

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.559

High

1036186

SMD1
Small nuclear ribonucleoprotein Sm D1

2

0

High-throughput

0.559

High

1038542

SLU7
Pre-mRNA-splicing factor SLU7

2

0

High-throughput

0.559

High

1065116

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.559

High

826380

SGN1
RNA-binding protein SGN1

1

17

High-throughput

0.553

High

1065112

PUF2
mRNA-binding protein PUF2

1

8

High-throughput

0.553

High

525427

HSP71
Heat shock protein SSA1

2

6

High-throughput

0.552

High

546602

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

865429

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.493

High

744216

RAD24
Checkpoint protein RAD24

1

0

Small-scale

0.486

High

826412

MPH1
ATP-dependent DNA helicase MPH1

1

17

Small-scale

0.481

High

590227

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

9

High-throughput

0.479

High

614853

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

1

High-throughput

0.479

High

627874

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

4

High-throughput

0.479

High

638020

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

11

Small-scale

0.479

High

643673

SNF2
Transcription regulatory protein SNF2

1

12

High-throughput

0.479

High

645555

XRN1
5'-3' exoribonuclease 1

1

6

High-throughput

0.479

High

666564

DBP2
ATP-dependent RNA helicase DBP2

1

9

High-throughput

0.479

High

671432

RNA14
mRNA 3'-end-processing protein RNA14

1

18

High-throughput

0.479

High

678754

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

High-throughput

0.479

High

700160

PRP45
Pre-mRNA-processing protein 45

1

3

High-throughput

0.479

High

708434

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

743058

SWI3
SWI/SNF complex subunit SWI3

1

2

High-throughput

0.479

High

758267

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.479

High

762876

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.479

High

794885

MAP2
Methionine aminopeptidase 2

1

2

High-throughput

0.479

High

795789

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

20

Small-scale

0.479

High

805648

LSM12
Protein LSM12

1

2

High-throughput

0.479

High

818066

LSM4
LSM complex subunit LSM4

1

2

High-throughput

0.479

High

853592

FIP1
Pre-mRNA polyadenylation factor FIP1

1

6

High-throughput

0.479

High

864542

MTR4
ATP-dependent RNA helicase DOB1

1

18

High-throughput

0.479

High

886358

PRP31
Pre-mRNA-processing factor 31

1

8

High-throughput

0.479

High

914885

CWC23
Pre-mRNA-splicing factor CWC23

1

3

High-throughput

0.479

High

919736

CWC22
Pre-mRNA-splicing factor CWC22

1

1

High-throughput

0.479

High

923912

TEX1
Protein TEX1

1

4

High-throughput

0.479

High

933151

RUXF
Small nuclear ribonucleoprotein F

1

2

High-throughput

0.479

High

1042840

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

1

High-throughput

0.479

High

1059349

BRE1
E3 ubiquitin-protein ligase BRE1

1

9

High-throughput

0.479

High

1062806

REXO4
RNA exonuclease 4

1

3

High-throughput

0.479

High

1065109

NOP53
Ribosome biogenesis protein NOP53

1

2

High-throughput

0.479

High

1065110

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

1065118

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1065119

NOP56
Nucleolar protein 56

1

8

High-throughput

0.479

High

1065126

NOP14
Nucleolar complex protein 14

1

1

High-throughput

0.479

High

1065113

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

617822

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.458

High

632119

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

672082

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

673132

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.458

High

752052

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.458

High

758053

MTR2
mRNA transport regulator MTR2

1

0

Small-scale

0.458

High

797326

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

797697

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

798625

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

805763

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

806593

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

849631

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

0

High-throughput

0.458

High

858369

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

919226

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

919564

SDA1
Protein SDA1

1

0

High-throughput

0.458

High

924166

SWT21
Protein SWT21

1

0

High-throughput

0.458

High

1026951

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

1042458

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

High-throughput

0.458

High

1048783

GFD1
mRNA transport factor GFD1

1

0

High-throughput

0.458

High

1053149

BUR2
Protein BUR2

1

0

Small-scale

0.458

High

1055001

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.458

High

1062928

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

1065108

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.458

High

792996

ANM1
Protein arginine N-methyltransferase 1

1

15

High-throughput

0.457

High

527916

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

820022

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

1042392

GCN5
Histone acetyltransferase GCN5

1

10

High-throughput

0.445

High

830030

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.438

High

555165

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.437

High

585403

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

4

High-throughput

0.437

High

628239

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

9

High-throughput

0.437

High

632602

DBP3
ATP-dependent RNA helicase DBP3

1

11

High-throughput

0.437

High

632925

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

1

High-throughput

0.437

High

634289

NUP1
Nucleoporin NUP1

1

8

High-throughput

0.437

High

639086

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.437

High

677604

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.437

High

700307

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

1

High-throughput

0.437

High

735466

AAR2
A1 cistron-splicing factor AAR2

1

1

High-throughput

0.437

High

738274

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

3

High-throughput

0.437

High

751505

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

2

High-throughput

0.437

High

795574

ATG8
Autophagy-related protein 8

1

14

High-throughput

0.437

High

812129

DHH1
ATP-dependent RNA helicase DHH1

1

18

High-throughput

0.437

High

829856

PHB1
Prohibitin-1

1

10

High-throughput

0.437

High

917501

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

8

High-throughput

0.437

High

923144

BRE5
UBP3-associated protein BRE5

1

12

High-throughput

0.437

High

924655

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.437

High

1046075

DHR1
Probable ATP-dependent RNA helicase DHR1

1

10

High-throughput

0.437

High

1050198

RRP5
rRNA biogenesis protein RRP5

1

11

High-throughput

0.437

High

1053128

UTP13
U3 small nucleolar RNA-associated protein 13

1

9

High-throughput

0.437

High

1060831

RLP24
Ribosome biogenesis protein RLP24

1

2

High-throughput

0.437

High

1065120

AIR2
Protein AIR2

1

6

High-throughput

0.437

High

1065121

NOP58
Nucleolar protein 58

1

8

High-throughput

0.437

High

1065122

EFG1P
rRNA-processing protein EFG1

1

1

High-throughput

0.437

High

510883

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.407

High

554060

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.407

High

671731

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.407

High

810779

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.407

High

811059

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.407

High

816453

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.407

High

893173

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

3

High-throughput

0.407

High

893247

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.407

High

1065115

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

1043893

NAB6
RNA-binding protein NAB6

2

0

High-throughput

0.328

High

1065124

BRR1
Pre-mRNA-splicing factor BRR1

2

0

High-throughput

0.305

High

533497

TIR1
Cold shock-induced protein TIR1

1

0

Small-scale

0.269

Low

618629

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.249

Low

794125

FAT2
Oxalate--CoA ligase

1

0

High-throughput

0.249

Low

826284

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.249

Low

863230

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.249

Low

1040700

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.249

Low

1043478

TCB3
Tricalbin-3

1

0

High-throughput

0.249

Low

1059615

NOP6
Nucleolar protein 6

1

0

High-throughput

0.249

Low

1065123

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.249

Low

1065128

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025