HitPredict

Interactor 1: AP2A (P05549)
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
Gene: TFAP2A

Interactor 2: CITE2 (Q99967)
Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)
Gene: CITED2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

The method score is based on:

Property	Details
Experiments	12586840, 11744733
Identification Methods	far western blotting, two hybrid, pull down
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 6 others more... GO:0010628 - positive regulation of gene expression GO:0043066 - negative regulation of apoptotic process GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060349 - bone morphogenesis
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	437
Hs

1	270

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024