HitPredict

Interactor 1: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005681 - spliceosomal complex GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 315
+	Hs
		236203 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Hs
		911713 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		903089 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Sp
		195196 RUXE_SCHPO (9-90): 7.25e-37: 120: 54.88		PRP17_SCHPO (224-306): 1.02e-11: 67.5: 16.47