HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016192 - vesicle-mediated transport GO:0048488 - synaptic vesicle endocytosis
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 116
+	Hs
		850553 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Sc
		503059 ARF1_YEAST (2-175): 2.05e-68: 207: 66.09		SNC1_YEAST (3-98): 2.69e-26: 96.3: 32.29
+	Hs
		261648 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		918878 RAB1A_HUMAN (1-174): 6.74e-67: 204: 18.99		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		1079428 RAB1B_HUMAN (10-174): 1.3e-66: 203: 19.41		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		263214 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180854 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		912923 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		913081 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50