HitPredict

Interactor 1: E5RI47 (E5RI47)
MAGUK p55 scaffold protein 2
Gene: MPP2

Interactor 2: LIN7B (Q9HAP6)
Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2)
Gene: LIN7B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	L27~L27, PDZ~PDZ
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 207
+	Hs
		1050415 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7B_HUMAN (1-207): 8.65e-63: 195: 100.00
+	Hs
		1334778 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7B_HUMAN (1-207): 8.65e-63: 195: 100.00
+	Hs
		1050418 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7C_HUMAN (1-196): 9.63e-58: 182: 84.69
+	Hs
		91354 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		LIN7C_HUMAN (1-196): 9.63e-58: 182: 84.69
+	Hs
		1346107 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7C_HUMAN (1-196): 9.63e-58: 182: 84.69
+	Hs
		158282 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7A_HUMAN (4-194): 1.18e-52: 170: 79.06
+	Hs
		159269 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7B_HUMAN (1-207): 8.65e-63: 195: 100.00
+	Hs
		91342 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		LIN7A_HUMAN (4-194): 1.18e-52: 170: 79.06
+	Hs
		158304 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7A_HUMAN (4-194): 1.18e-52: 170: 79.06
+	Hs
		159277 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7C_HUMAN (1-196): 9.63e-58: 182: 84.69
+	Hs
		158254 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7A_HUMAN (4-194): 1.18e-52: 170: 79.06
+	Mm
		1143555 MPP2_MOUSE (1-189): 9.84e-76: 238: 94.36		DLG4_MOUSE (86-206): 2.01e-24: 102: 27.78
+	Hs
		159203 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		SNTB2_HUMAN (2-207): 1.48e-36: 135: 28.10
+	Hs
		159207 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		SNTB1_HUMAN (2-206): 4.53e-34: 128: 23.94
+	Hs
		1021489 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		DLG1_HUMAN (59-180): 1.67e-23: 99.4: 29.92
+	Hs
		159110 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		CSKP_HUMAN (10-206): 4.77e-31: 121: 20.00
+	Hs
		91344 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		DLG1_HUMAN (59-180): 1.67e-23: 99.4: 29.92
+	Hs
		159190 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG4_HUMAN (86-206): 6.05e-24: 100: 27.78
+	Hs
		159200 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG1_HUMAN (59-180): 1.67e-23: 99.4: 29.92
+	Hs
		159249 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG3_HUMAN (29-164): 2.29e-20: 90.3: 25.53