HitPredict

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: 2ABD (Q66LE6)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)
Gene: PPP2R2D

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.740

Property	Details
Experiments	28330616, 33961781, 19156129, 26186194, 27880917, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000159 - protein phosphatase type 2A complex GO:0000278 - mitotic cell cycle GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Hs			1 453
+	Hs
		930887 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABD_HUMAN (1-453): 0: 873: 100.00
+	Hs
		890977 PP4C_HUMAN (4-309): 0: 511: 64.50		2ABD_HUMAN (1-453): 0: 873: 100.00
+	Hs
		927793 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABA_HUMAN (1-453): 0: 838: 87.86
+	Hs
		915156 PP2AB_HUMAN (1-309): 0: 532: 100.00		2ABA_HUMAN (1-453): 0: 838: 87.86
+	Mm
		915330 PP2AB_MOUSE (1-309): 0: 532: 100.00		2ABA_MOUSE (1-453): 0: 838: 87.86
+	Xl
		1153591 Q8AVH9_XENLA (1-309): 0: 530: 97.41		Q6IRD3_XENLA (1-453): 0: 827: 84.99
+	Hs
		890945 PP4C_HUMAN (4-309): 0: 511: 64.50		2ABA_HUMAN (1-453): 0: 838: 87.86
+	Hs
		930805 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Hs
		915163 PP2AB_HUMAN (1-309): 0: 532: 100.00		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Dm
		619858 PP2A_DROME (1-309): 0: 527: 94.50		2ABA_DROME (6-451): 0: 805: 78.25
+	Xl
		50761 Q92140_XENLA (1-309): 0: 531: 98.06		2ABB_XENLA (32-453): 0: 794: 87.92
+	Xl
		50750 Q8AVH9_XENLA (1-309): 0: 530: 97.41		2ABB_XENLA (32-453): 0: 794: 87.92
+	Hs
		931049 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Hs
		915310 PP2AB_HUMAN (1-309): 0: 532: 100.00		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Hs
		890952 PP4C_HUMAN (4-309): 0: 511: 64.50		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Hs
		891015 PP4C_HUMAN (4-309): 0: 511: 64.50		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Ce
		106202 PP2A_CAEEL (3-309): 0: 523: 89.58		2AB1_CAEEL (12-450): 0: 707: 65.20
+	Sp
		619316 PP2A2_SCHPO (5-309): 0: 507: 79.02		2ABA_SCHPO (17-449): 0: 668: 56.30
+	Sc
		618856 PP2A2_YEAST (9-309): 0: 531: 76.08		2ABA_YEAST (382-449): 2.2e-09: 61.6: 38.57
+	Sc
		618793 PP2A1_YEAST (7-309): 0: 519: 74.92		2ABA_YEAST (382-449): 2.2e-09: 61.6: 38.57