HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: SI1L2 (Q9P2F8)
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)
Gene: SIPA1L2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, Rap_GAP~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1722
+	Hs
		196428 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SI1L1_HUMAN (1-1719): 0: 1424: 48.02
+	Hs
		230233 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Hs
		230232 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SI1L3_HUMAN (19-1714): 0: 1313: 42.85
+	Dm
		776929 RAC1_DROME (1-196): 1.58e-77: 231: 53.06		X2JDH0_DROME (439-827): 4.61e-110: 390: 34.68
+	Dm
		776932 RAC1_DROME (1-196): 1.58e-77: 231: 53.06		X2JJU0_DROME (439-827): 4.04e-110: 390: 34.68
+	Hs
		835036 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TSC2_HUMAN (538-860): 1.95e-102: 367: 21.07
+	Hs
		915714 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RGPA2_HUMAN (502-852): 1.14e-101: 364: 21.63
+	Hs
		951036 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		RGPA2_HUMAN (502-852): 1.14e-101: 364: 21.63
+	Hs
		925359 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RGPA1_HUMAN (504-833): 7.23e-95: 343: 22.99
+	Hs
		900583 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RGPA1_HUMAN (504-833): 7.23e-95: 343: 22.99
+	Hs
		915756 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RGPA1_HUMAN (504-833): 7.23e-95: 343: 22.99
+	Hs
		925690 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG23_HUMAN (960-1528): 4.6e-39: 162: 13.57
+	Hs
		901000 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RHG23_HUMAN (960-1528): 4.6e-39: 162: 13.57
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (1321-1712): 5.57e-22: 106: 8.52
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (1321-1712): 5.57e-22: 106: 8.52
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (1321-1712): 5.57e-22: 106: 8.52
+	Hs
		925514 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SIPA1_HUMAN (1389-1707): 1.51e-20: 101: 18.71
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (1321-1712): 5.57e-22: 106: 8.52
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (1321-1712): 5.57e-22: 106: 8.52
+	Hs
		900790 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SIPA1_HUMAN (1389-1707): 1.51e-20: 101: 18.71