HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: RAB23 (Q9ULC3)
Ras-related protein Rab-23
Gene: RAB23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport and 1 others more... GO:0010008 - endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 237
+	Hs
		925294 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAB35_HUMAN (2-179): 1.06e-94: 277: 35.96
+	Hs
		900494 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RAB35_HUMAN (2-179): 1.06e-94: 277: 35.96
+	Hs
		915691 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB35_HUMAN (2-179): 1.06e-94: 277: 35.96
+	Hs
		918847 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		925600 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAB1B_HUMAN (2-201): 1.76e-85: 254: 31.34
+	Hs
		900355 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		915582 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		925719 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAB23_HUMAN (1-237): 1.39e-84: 253: 100.00
+	Hs
		900882 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RAB1B_HUMAN (2-201): 1.76e-85: 254: 31.34
+	Hs
		894716 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		913995 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RB11A_HUMAN (3-210): 2.35e-83: 249: 29.67
+	Hs
		894710 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		894714 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		913991 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RB11A_HUMAN (3-210): 2.35e-83: 249: 29.67
+	Hs
		915883 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB8B_HUMAN (2-200): 1.45e-83: 249: 30.50
+	Hs
		895473 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB10_HUMAN (1-209): 7.43e-83: 247: 30.48
+	Hs
		844863 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47
+	Hs
		845846 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB13_HUMAN (11-172): 4.05e-34: 123: 37.42
+	Hs
		844856 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47
+	Hs
		844860 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47