HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 486
+	Hs
		925732 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		901050 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		951457 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		925717 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		901035 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		916063 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		925230 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		925414 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		NOSTN_HUMAN (24-485): 3.12e-47: 172: 16.13
+	Hs
		915631 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		545343 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		950948 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		925540 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		915910 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		951252 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		925240 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		900425 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		915640 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		545347 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		950955 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		925339 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		FBP1L_HUMAN (300-482): 7.32e-09: 60.2: 19.05