HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: TBD2B (Q9UPU7)
TBC1 domain family member 2B
Gene: TBC1D2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, RabGAP-TBC~Ras
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 963
+	Hs
		925738 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TBD2B_HUMAN (32-963): 0: 778: 100.00
+	Hs
		951462 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		TBD2B_HUMAN (32-963): 0: 778: 100.00
+	Hs
		892684 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		TBD2B_HUMAN (32-963): 0: 778: 100.00
+	Hs
		894392 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBD2A_HUMAN (1-962): 0: 627: 38.31
+	Ce
		975574 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		Q23419_CAEEL (23-929): 0: 556: 27.06
+	Hs
		925616 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		900902 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		951339 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		892596 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		894431 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		232655 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBCD4_HUMAN (372-959): 2e-99: 341: 16.80
+	Hs
		925323 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TB10B_HUMAN (294-950): 2.55e-95: 321: 17.02
+	Hs
		915717 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TB10B_HUMAN (294-950): 2.55e-95: 321: 17.02
+	Hs
		892404 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		TB10B_HUMAN (294-950): 2.55e-95: 321: 17.02
+	Hs
		915938 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TB10A_HUMAN (540-936): 2.11e-91: 301: 24.25
+	Mm
		925784 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		EVI5_MOUSE (590-962): 2.57e-86: 296: 19.58
+	Hs
		564554 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		TB10B_HUMAN (294-950): 2.55e-95: 321: 17.02
+	Hs
		321279 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBCD8_HUMAN (608-960): 5.25e-85: 299: 26.80
+	Sc
		419713 RHO1_YEAST (3-186): 1.7e-88: 260: 67.39		GYP3_YEAST (652-962): 1.48e-26: 118: 29.29