HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: TTF2 (Q9UNY4)
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
Gene: TTF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1162
+	Hs
		917182 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		846914 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Hs
		917635 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD6_HUMAN (101-1160): 0: 591: 14.77
+	Hs
		918062 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD7_HUMAN (93-1160): 9.11e-179: 585: 15.23
+	Hs
		917965 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD8_HUMAN (93-1160): 2.85e-177: 579: 15.22
+	Hs
		917364 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD9_HUMAN (88-1160): 5.02e-175: 574: 15.55
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Hs
		151483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD2_HUMAN (67-1151): 2.51e-177: 570: 17.29
+	Hs
		229352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Dm
		950383 H4_DROME (1-103): 4.51e-48: 150: 99.03		ISWI_DROME (450-1158): 2.07e-174: 542: 19.40
+	Hs
		918003 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HELLS_HUMAN (378-1160): 8.61e-176: 540: 18.30
+	Sc
		356774 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW2_YEAST (385-1159): 5.78e-170: 533: 19.27
+	Sc
		356424 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW1_YEAST (497-1150): 3.01e-169: 532: 21.94
+	Sc
		356315 H4_YEAST (18-103): 6.13e-41: 132: 90.70		BTAF1_YEAST (554-1160): 4.42e-160: 523: 24.92
+	Sc
		356551 H4_YEAST (18-103): 6.13e-41: 132: 90.70		IRC5_YEAST (550-1159): 6.12e-165: 512: 23.14
+	Sc
		356309 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RAD16_YEAST (529-1160): 3.17e-161: 500: 25.84
+	Hs
		917261 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HLTF_HUMAN (618-1137): 2.01e-68: 251: 30.52
+	Sp
		194289 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		FFT3_SCHPO (548-1148): 4.54e-34: 144: 26.70