Protein: ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating (EC 1.1.1.170) (C-3 sterol dehydrogenase ERG26) (C-4 decarboxylase ERG26) (Ergosterol biosynthetic protein 26)

Gene: ERG26
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P53199

Gene Ontology (top 5):
GO:0000252 - 3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006696 - ergosterol biosynthetic process
GO:0102175 - 3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817335

ERG28
Ergosterol biosynthetic protein 28

3

1

Small-scale

0.670

High

916767

ERG25
C-4 methylsterol oxidase ERG25

3

2

Small-scale

0.660

High

715043

ERG9
Squalene synthase ERG9

2

2

Small-scale

0.614

High

737162

ERG24
Delta(14)-sterol reductase ERG24

2

3

Small-scale

0.614

High

528614

CP51
Lanosterol 14-alpha demethylase CYP51

1

3

Small-scale

0.541

High

672166

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

3

Small-scale

0.541

High

735350

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

2

Small-scale

0.541

High

918143

TMEDA
Endoplasmic reticulum vesicle protein 25

1

4

High-throughput

0.541

High

918154

ERG27
3-keto-steroid reductase ERG27

1

3

Small-scale

0.541

High

579781

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.533

High

668938

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

Small-scale

0.518

High

735319

ERG2
C-8 sterol isomerase ERG2

1

0

Small-scale

0.518

High

737580

ERG1
Squalene epoxidase ERG1

1

0

Small-scale

0.518

High

800448

ERG7
Lanosterol synthase ERG7

1

0

Small-scale

0.518

High

918149

ORM2
Protein ORM2

1

0

High-throughput

0.518

High

722115

XPO1
Exportin-1

1

2

High-throughput

0.489

High

679902

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

918148

ERP1
Protein ERP1

1

3

High-throughput

0.457

High

393071

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.437

High

670949

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

709885

BMH1
Protein BMH1

1

3

High-throughput

0.437

High

795114

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

850114

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

897482

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.437

High

918142

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.437

High

918145

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

High-throughput

0.437

High

918150

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

918151

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

918153

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

High-throughput

0.437

High

527245

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

819336

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

836802

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.407

High

794089

MCM7
DNA replication licensing factor MCM7

2

0

High-throughput

0.319

High

386800

TBB
Tubulin beta chain

1

0

High-throughput

0.279

Low

918152

MDN1
Midasin

1

0

High-throughput

0.279

Low

382958

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

435241

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

518341

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low

646472

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

707714

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

727199

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

778443

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

807832

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

812504

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

815183

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.249

Low

874430

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

918144

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

918146

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.249

Low

918147

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

394754

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

453702

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025