HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 482
+	Hs
		1038424 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270408 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		707620 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1087306 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		707699 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1038530 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270409 H2B1L_HUMAN (1-126): 2.18e-52: 163: 98.41		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1231218 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1038606 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270361 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		177352 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	At
		1322590 H2B10_ARATH (3-125): 9.62e-44: 141: 58.99		HDA6_ARATH (5-461): 0: 578: 58.04
+	Sp
		140569 H2B1_SCHPO (4-125): 1.06e-45: 146: 70.49		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		355947 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Sc
		355966 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		HDA1_YEAST (10-329): 4.19e-119: 366: 26.74
+	Hs
		1307130 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		241656 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		707778 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		886211 H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		1307148 H2B1L_HUMAN (1-126): 2.18e-52: 163: 98.41		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78