HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: MARH7 (Q9H992)
E3 ubiquitin-protein ligase MARCHF7 (EC 2.3.2.27) (Axotrophin) (Membrane-associated RING finger protein 7) (Membrane-associated RING-CH protein VII) (MARCH-VII) (RING finger protein 177) (RING-type E3 ubiquitin transferase MARCHF7)
Gene: MARCHF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	24905733
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 704
+	Hs
		849448 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MARH7_HUMAN (1-704): 0: 942: 100.00
+	Hs
		895915 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		MARH7_HUMAN (1-704): 0: 942: 100.00
+	Hs
		851887 UB2E1_HUMAN (4-146): 8.81e-73: 217: 65.73		MARH7_HUMAN (1-704): 0: 942: 100.00
+	Hs
		896544 UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22		MARH7_HUMAN (1-704): 0: 942: 100.00
+	Hs
		1199325 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		MARH3_HUMAN (490-681): 1.84e-57: 197: 18.09
+	Hs
		919767 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		MARH3_HUMAN (490-681): 1.84e-57: 197: 18.09
+	Hs
		895832 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		MARH3_HUMAN (490-681): 1.84e-57: 197: 18.09
+	Hs
		849466 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MARH2_HUMAN (490-681): 5.49e-52: 182: 19.60
+	Hs
		1199317 UB2E2_HUMAN (4-146): 5.85e-75: 223: 65.73		MARH3_HUMAN (490-681): 1.84e-57: 197: 18.09
+	Hs
		851833 UB2E1_HUMAN (4-146): 8.81e-73: 217: 65.73		MARH3_HUMAN (490-681): 1.84e-57: 197: 18.09
+	Hs
		849378 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MARH1_HUMAN (490-647): 1.35e-47: 171: 22.15
+	Hs
		851897 UB2E1_HUMAN (4-146): 8.81e-73: 217: 65.73		MARH2_HUMAN (490-681): 5.49e-52: 182: 19.60
+	Hs
		849338 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MARH8_HUMAN (505-647): 6.68e-37: 141: 20.98
+	Hs
		895806 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		MARH8_HUMAN (505-647): 6.68e-37: 141: 20.98
+	Hs
		849469 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MARH4_HUMAN (538-647): 2.16e-27: 117: 22.52
+	Hs
		231862 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		MARH6_HUMAN (544-620): 1.64e-19: 95.7: 28.57
+	Zm
		35750 A0A1D6LTJ2_MAIZE (1-112): 4.05e-60: 184: 75.00		A0A1D6LR06_MAIZE (551-649): 5.5e-18: 90.7: 25.25