HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 449
+	Hs
		924459 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		924458 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428131 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		924460 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		411549 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		411668 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933439 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		782771 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		933201 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		557723 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428198 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933801 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		548680 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		548729 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		522894 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		433849 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		548725 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBA3E_HUMAN (1-439): 0: 700: 96.13
+	Hs
		428001 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		548681 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		427991 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		TBB5_HUMAN (1-439): 0: 699: 41.00