HitPredict

Interactor 1: HDA1 (P53973)
Histone deacetylase HDA1 (EC 3.5.1.98)
Gene: HDA1

Interactor 2: HDA1 (P53973)
Histone deacetylase HDA1 (EC 3.5.1.98)
Gene: HDA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 27665728, 18719252, 19573535, 21179020, 11287668
Identification Methods pull down, x-ray crystallography, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arb2-like~Arb2-like, Arb2-like~Hist_deacetyl, Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0040029 - epigenetic regulation of gene expression
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 706
Sc

1 706
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Service provided by Combinatics, Japan

Last updated: 11Aug2025