HitPredict

Interactor 1: MK01 (P63085)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Interactor 2: Q99K94 (Q99K94)
Signal transducer and activator of transcription
Gene: Stat1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	18378670
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 358 Mm			1 712
+	Hs
		658828 MK01_HUMAN (9-358): 5.56e-158: 448: 99.71		STAT1_HUMAN (1-712): 0: 932: 93.68
+	Hs
		658824 MK01_HUMAN (9-358): 5.56e-158: 448: 99.71		STAT3_HUMAN (1-710): 0: 858: 53.70
+	Hs
		647492 MK03_HUMAN (3-356): 7.99e-154: 439: 85.88		STAT3_HUMAN (1-710): 0: 858: 53.70
+	Mm
		786542 MK03_MOUSE (13-355): 3.86e-153: 437: 88.34		STAT3_MOUSE (1-710): 0: 859: 53.70
+	Hs
		658829 MK01_HUMAN (9-358): 5.56e-158: 448: 99.71		STA5A_HUMAN (1-710): 0: 736: 29.70