HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: ACTG (P63260)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: Actg1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 245 Mm			1 375
+	Mm
		935546 1433F_MOUSE (2-240): 5.1e-108: 313: 74.07		ACTBL_MOUSE (1-375): 0: 741: 92.27
+	Hs
		891673 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		926908 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		891665 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Mm
		926769 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ACTS_MOUSE (2-375): 0: 594: 93.85
+	Hs
		926910 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		646763 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		646783 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		915357 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		909433 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		646777 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		683256 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		904433 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		683952 1433S_HUMAN (1-237): 2.52e-103: 301: 71.55		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		683941 1433S_HUMAN (1-237): 2.52e-103: 301: 71.55		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		683954 1433S_HUMAN (1-237): 2.52e-103: 301: 71.55		ACTS_HUMAN (2-375): 0: 594: 93.85