HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: PDE4D (Q01063)
3',5'-cyclic-AMP phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (cAMP-specific phosphodiesterase 4D)
Gene: PDE4D

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0044325 - transmembrane transporter binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Mm			1 747
+	Mm
		926801 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		PDE1A_MOUSE (206-638): 1.37e-150: 451: 30.97
+	Hs
		872399 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE1A_HUMAN (223-638): 6.65e-151: 452: 32.32
+	Mm
		926779 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		PDE1B_MOUSE (223-722): 1.26e-147: 443: 28.63
+	Hs
		927558 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE7B_HUMAN (293-674): 8.31e-143: 428: 32.82
+	Hs
		910054 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDE7B_HUMAN (293-674): 8.31e-143: 428: 32.82
+	Hs
		927008 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE3B_HUMAN (20-726): 5.12e-133: 423: 23.88
+	Hs
		909520 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDE3B_HUMAN (20-726): 5.12e-133: 423: 23.88
+	Hs
		647301 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PDE7B_HUMAN (293-674): 8.31e-143: 428: 32.82
+	Hs
		683736 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		PDE7B_HUMAN (293-674): 8.31e-143: 428: 32.82
+	Hs
		927039 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE3A_HUMAN (259-723): 8.62e-130: 415: 24.90
+	Hs
		646867 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PDE3B_HUMAN (20-726): 5.12e-133: 423: 23.88
+	Hs
		646886 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PDE3A_HUMAN (259-723): 8.62e-130: 415: 24.90
+	Hs
		927028 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE7A_HUMAN (260-661): 2.84e-132: 402: 30.05
+	Hs
		909546 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDE7A_HUMAN (260-661): 2.84e-132: 402: 30.05
+	Hs
		683334 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		PDE7A_HUMAN (260-661): 2.84e-132: 402: 30.05
+	Hs
		905142 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		PDE7B_HUMAN (293-674): 8.31e-143: 428: 32.82
+	Hs
		904523 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		PDE3B_HUMAN (20-726): 5.12e-133: 423: 23.88
+	Hs
		981979 1433F_HUMAN (2-240): 5.21e-108: 313: 74.49		PDE3B_HUMAN (20-726): 5.12e-133: 423: 23.88