Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1
Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 1.00 | 0.996 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25332235, 25900982, 25632159, 26474281, 15536641, 28614300, 30267325, 29863914, 30254149, 29997244, 12609982, 31210753, 10644755, 10918611, 9660940, 32350066, 10531035, 35813202, 36044955, 36289220 and 31 others
more... |
| Identification Methods | affinity chromatography technology, proximity labelling technology, pull down, fluorescent resonance energy transfer, two hybrid, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, mammalian protein protein interaction trap, luminescence based mammalian interactome mapping and 4 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | F-box-like~Skp1 |
| Common GO terms | GO:0000209 - protein polyubiquitination GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008013 - beta-catenin binding and 7 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
