HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 718
+	Hs
		724859 ACTBL_HUMAN (2-375): 0: 734: 91.44		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Dm
		115212 ACT1_DROME (2-375): 0: 600: 98.13		M9PEG0_DROME (11-706): 2.96e-37: 152: 16.97
+	Hs
		915435 ACTA_HUMAN (2-375): 0: 594: 94.39		K2C78_HUMAN (276-606): 5.85e-21: 99.3: 19.53
+	Rn
		892236 ACTB_RAT (1-375): 0: 604: 98.93		MYH10_RAT (308-718): 1.61e-15: 83.1: 10.46
+	Hs
		929935 ACTG_HUMAN (1-375): 0: 604: 100.00		DLG5_HUMAN (171-610): 2.12e-15: 82.7: 17.71
+	Hs
		725136 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71
+	Hs
		725135 ACTH_HUMAN (2-375): 0: 592: 94.39		MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71
+	Hs
		891935 ACTB_HUMAN (1-375): 0: 604: 98.93		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Rn
		892228 ACTB_RAT (1-375): 0: 604: 98.93		MYH9_RAT (401-717): 1.3e-09: 63.8: 11.36
+	Hs
		929952 ACTG_HUMAN (1-375): 0: 604: 100.00		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		892003 ACTB_HUMAN (1-375): 0: 604: 98.93		CP250_HUMAN (36-648): 2.21e-09: 63.5: 11.38
+	Mm
		892205 ACTB_MOUSE (1-375): 0: 604: 98.93		MYH9_MOUSE (23-360): 3.62e-09: 62.7: 10.99
+	Hs
		724738 ACTB_HUMAN (1-375): 0: 604: 98.93		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		724762 ACTG_HUMAN (1-375): 0: 604: 100.00		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		915524 ACTA_HUMAN (2-375): 0: 594: 94.39		DAPLE_HUMAN (58-493): 1.77e-11: 70.2: 12.07
+	Hs
		932297 ACTC_HUMAN (2-375): 0: 595: 94.39		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		933030 ACTS_HUMAN (2-375): 0: 594: 93.85		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		724766 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		724767 ACTS_HUMAN (2-375): 0: 594: 93.85		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27