Protein: PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2 (EC 3.1.3.16) (Calcineurin A2) (Calmodulin-binding protein 2)

Gene: PP2B2, CMP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P14747

Gene Ontology (top 5):
GO:0000747 - conjugation with cellular fusion
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005955 - calcineurin complex
GO:0006873 - intracellular monoatomic ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449049

CALM
Calmodulin

6

18

Small-scale

0.947

High

575569

CANB
Calcineurin subunit B

6

20

High-throughput

0.942

High

575568

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

2

13

Small-scale

0.755

High

392140

HSP82
ATP-dependent molecular chaperone HSP82

2

5

Small-scale

0.754

High

575603

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

2

5

Small-scale

0.629

High

575564

HSC82
ATP-dependent molecular chaperone HSC82

1

5

Small-scale

0.618

High

575581

RCN1
Calcipressin-like protein

2

1

Small-scale

0.595

High

575600

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

575624

RUVB2
RuvB-like protein 2

2

6

High-throughput

0.565

High

522924

HSP71
Heat shock protein SSA1

2

14

High-throughput

0.552

High

575595

SSB2
Ribosome-associated molecular chaperone SSB2

2

15

High-throughput

0.552

High

560640

KIN2
Serine/threonine-protein kinase KIN2

1

6

High-throughput

0.536

High

575580

EF1G2
Elongation factor 1-gamma 2

1

3

High-throughput

0.536

High

575587

KSP1
Serine/threonine-protein kinase KSP1

1

13

High-throughput

0.536

High

575615

RGC1
Regulator of the glycerol channel 1

1

5

High-throughput

0.536

High

575626

HPH1
Protein HPH1

2

1

Small-scale

0.535

High

575565

GCN2
eIF-2-alpha kinase GCN2

1

9

High-throughput

0.515

High

558548

CAF20
Cap-associated protein CAF20

1

2

Small-scale

0.501

High

575574

MLF3
Protein MLF3

1

1

Small-scale

0.501

High

575575

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

6

Small-scale

0.501

High

575577

ELM1
Serine/threonine-protein kinase ELM1

1

2

Small-scale

0.501

High

575582

ALY1
Arrestin-related trafficking adapter 6

1

4

Small-scale

0.501

High

575588

KIC1
Serine/threonine-protein kinase KIC1

1

11

Small-scale

0.501

High

575597

RTS2
Zinc finger protein RTS2

1

1

Small-scale

0.501

High

575599

STB1
Protein STB1

1

1

Small-scale

0.501

High

575604

CRZ1
Transcriptional regulator CRZ1

1

3

Small-scale

0.501

High

575605

ROD1
Protein ROD1

1

4

Small-scale

0.501

High

575608

DIG2
Down-regulator of invasive growth 2

1

1

Small-scale

0.501

High

575609

TDA1
Serine/threonine-protein kinase TDA1

1

10

Small-scale

0.501

High

575610

LIC4
Protein ATC1/LIC4

1

1

Small-scale

0.501

High

575616

SKG3
Protein SKG3

1

1

Small-scale

0.501

High

575617

RGA2
Rho-type GTPase-activating protein 2

1

5

Small-scale

0.501

High

575619

TFB6
General transcription and DNA repair factor IIH subunit TFB6

1

1

Small-scale

0.501

High

575621

RCN2
Regulator of calcineurin 2

1

1

Small-scale

0.501

High

575625

YP247
WD repeat-containing protein YPL247C

1

11

Small-scale

0.501

High

432280

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

1

High-throughput

0.500

High

453397

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.500

High

575566

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.500

High

575601

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

4

High-throughput

0.489

High

575596

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

5

Small-scale

0.481

High

408280

GAL1
Galactokinase

1

0

High-throughput

0.479

High

531228

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

575598

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.479

High

575570

BPH1
Beige protein homolog 1

1

5

High-throughput

0.479

High

575583

ATG8
Autophagy-related protein 8

1

5

High-throughput

0.479

High

575589

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

575623

INP53
Polyphosphatidylinositol phosphatase INP53

1

3

Small-scale

0.479

High

575578

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

531585

RL4A
Large ribosomal subunit protein uL4A

1

2

Small-scale

0.457

High

575576

SRP40
Suppressor protein SRP40

1

8

Small-scale

0.457

High

575584

YB75
Uncharacterized protein YBR225W

1

2

Small-scale

0.457

High

575585

UBX7
UBX domain-containing protein 7

1

5

Small-scale

0.457

High

575590

SFB3
SED5-binding protein 3

1

1

Small-scale

0.457

High

575591

SPT8
SAGA complex subunit SPT8

1

1

Small-scale

0.457

High

575592

UME6
Transcriptional regulatory protein UME6

1

1

Small-scale

0.457

High

575593

NUP60
Nucleoporin NUP60

1

1

Small-scale

0.457

High

575602

ZRG17
Protein ZRG17

1

1

Small-scale

0.457

High

575607

JIP4
Uncharacterized protein JIP4

1

3

Small-scale

0.457

High

575618

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.457

High

366907

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.457

High

405011

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.457

High

575567

HSP60
Heat shock protein 60, mitochondrial

1

3

High-throughput

0.457

High

440890

CDC7
Cell division control protein 7

1

20

Small-scale

0.445

High

525813

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

543676

SSB1
Ribosome-associated molecular chaperone SSB1

1

15

High-throughput

0.445

High

575579

SPT7
SAGA complex subunit SPT7

1

10

High-throughput

0.445

High

575594

FIR1
Factor interacting with REF2

1

2

Small-scale

0.439

High

575573

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

575620

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

575611

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

575606

GCN5
Histone acetyltransferase GCN5

1

8

High-throughput

0.407

High

575622

HFI1
SAGA complex subunit HFI1

1

1

High-throughput

0.407

High

575572

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

0

High-throughput

0.279

Low

575586

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.279

Low

575614

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.279

Low

575571

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.261

Low

575612

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

575613

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025