HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005925 - focal adhesion
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 559
+	Rn
		892225 ACTB_RAT (1-375): 0: 604: 98.93		WASF1_RAT (1-559): 1.61e-69: 235: 97.50
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 734: 91.44		MUC1_HUMAN (188-550): 1.54e-14: 79: 12.95
+	Hs
		930055 ACTG_HUMAN (1-375): 0: 604: 100.00		WASF3_HUMAN (1-557): 1.12e-43: 164: 45.73
+	Hs
		892150 ACTB_HUMAN (1-375): 0: 604: 98.93		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		930077 ACTG_HUMAN (1-375): 0: 604: 100.00		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		932482 ACTC_HUMAN (2-375): 0: 595: 94.39		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		891726 ACTB_HUMAN (1-375): 0: 604: 98.93		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		915369 ACTA_HUMAN (2-375): 0: 594: 94.39		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		932966 ACTS_HUMAN (2-375): 0: 594: 93.85		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 594: 94.39		MUC1_HUMAN (188-550): 1.54e-14: 79: 12.95
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 595: 94.39		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53