HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: WASF3 (Q9UPY6)
Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3)
Gene: WASF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005856 - cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 502
+	Hs
		929950 ACTG_HUMAN (1-375): 0: 604: 100.00		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 734: 91.44		MUC1_HUMAN (77-452): 1.55e-13: 75.5: 11.00
+	Hs
		892150 ACTB_HUMAN (1-375): 0: 604: 98.93		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Hs
		930077 ACTG_HUMAN (1-375): 0: 604: 100.00		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Rn
		892225 ACTB_RAT (1-375): 0: 604: 98.93		WASF1_RAT (1-500): 1.87e-56: 199: 43.04
+	Hs
		932482 ACTC_HUMAN (2-375): 0: 595: 94.39		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 595: 94.39		SYNJ1_HUMAN (11-499): 4.06e-38: 151: 11.82
+	Hs
		891942 ACTB_HUMAN (1-375): 0: 604: 98.93		CBP_HUMAN (153-498): 1.18e-22: 104: 13.84
+	Hs
		915464 ACTA_HUMAN (2-375): 0: 594: 94.39		CBP_HUMAN (153-498): 1.18e-22: 104: 13.84
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 594: 94.39		MUC1_HUMAN (77-452): 1.55e-13: 75.5: 11.00