HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: NACC1 (Q96RE7)
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)
Gene: NACC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	25891951, 36527749
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 527
+	Hs
		1120773 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KLH12_HUMAN (10-268): 5.89e-67: 227: 18.63
+	Hs
		307160 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KLHL2_HUMAN (9-322): 4.22e-63: 218: 15.46
+	Hs
		930247 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		KLH12_HUMAN (10-268): 5.89e-67: 227: 18.63
+	Hs
		895941 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		KLHL3_HUMAN (9-267): 3.35e-63: 218: 17.16
+	Hs
		307190 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		KLHL2_HUMAN (9-322): 4.22e-63: 218: 15.46
+	Hs
		307165 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		KLHL2_HUMAN (9-322): 4.22e-63: 218: 15.46
+	Hs
		849329 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		KEAP1_HUMAN (3-260): 7.39e-59: 207: 14.66
+	Hs
		312048 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZBT7A_HUMAN (1-431): 6.26e-61: 212: 16.86
+	Hs
		1183303 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		GMCL1_HUMAN (21-452): 1.18e-56: 199: 15.27
+	Hs
		930355 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		GMCL1_HUMAN (21-452): 1.18e-56: 199: 15.27
+	Hs
		983989 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		ZBT16_HUMAN (4-346): 1.57e-48: 180: 20.52
+	Hs
		930161 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZBT16_HUMAN (4-346): 1.57e-48: 180: 20.52
+	Dm
		639389 UBCD1_DROME (4-157): 4.5e-74: 220: 35.71		TTKA_DROME (2-354): 8.8e-43: 165: 15.17
+	Hs
		1183297 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		ZBTB9_HUMAN (3-295): 3.98e-43: 161: 21.24
+	Hs
		930214 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		HIC1_HUMAN (7-293): 1.5e-42: 163: 20.40
+	Hs
		930343 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZBTB9_HUMAN (3-295): 3.98e-43: 161: 21.24
+	Hs
		1183296 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		ZBT8A_HUMAN (7-188): 1.37e-41: 156: 26.09
+	Hs
		930342 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZBT8A_HUMAN (7-188): 1.37e-41: 156: 26.09
+	Hs
		1183282 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		ZBTB2_HUMAN (7-117): 8.4e-11: 66.2: 34.82
+	Hs
		930299 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZBTB2_HUMAN (7-117): 8.4e-11: 66.2: 34.82