HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	27780869
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 835
+	Hs
		915179 PP2AB_HUMAN (1-309): 0: 528: 97.41		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		890957 PP4C_HUMAN (4-309): 0: 508: 64.82		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		737784 PP1G_HUMAN (7-306): 0: 505: 45.96		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		905868 PP1A_HUMAN (5-296): 0: 504: 46.51		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		175667 PP2AA_HUMAN (1-309): 0: 529: 100.00		TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78
+	Hs
		175656 PP4C_HUMAN (4-309): 0: 508: 64.82		TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78
+	Hs
		891012 PP4C_HUMAN (4-309): 0: 508: 64.82		TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36
+	Hs
		906010 PP1A_HUMAN (5-296): 0: 504: 46.51		TRI42_HUMAN (18-491): 8.59e-48: 183: 14.96