HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: STRP1 (Q5VSL9)
Striatin-interacting protein 1 (Protein FAM40A)
Gene: STRIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.973

Property	Details
Experiments	18782753, 33961781, 26496610, 28330616, 35271311, 19156129, 25531779, 33633399
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUF3402~Metallophos, Metallophos~N1221
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 837
+	Hs
		915215 PP2AB_HUMAN (1-309): 0: 528: 97.41		STRP1_HUMAN (1-837): 0: 1350: 100.00
+	Hs
		931040 PP2AA_HUMAN (1-309): 0: 529: 100.00		STRP2_HUMAN (47-837): 0: 1209: 71.14
+	Hs
		915303 PP2AB_HUMAN (1-309): 0: 528: 97.41		STRP2_HUMAN (47-837): 0: 1209: 71.14
+	Sc
		618790 PP2A1_YEAST (10-309): 0: 517: 76.00		FAR11_YEAST (81-805): 3.1e-92: 312: 18.21
+	Sc
		618853 PP2A2_YEAST (10-309): 0: 514: 76.67		FAR11_YEAST (81-805): 3.1e-92: 312: 18.21