HitPredict

Interactor 1: YBOX1 (P67809)
Y-box-binding protein 1 (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Nuclease-sensitive element-binding protein 1) (Y-box transcription factor)
Gene: YBX1

Interactor 2: LARP1 (Q6PKG0)
La-related protein 1 (La ribonucleoprotein domain family member 1)
Gene: LARP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 23986595, 25497084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule GO:0017148 - negative regulation of translation and 1 others more... GO:0048255 - mRNA stabilization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 324 Hs			1 1096
+	Hs
		1162585 LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		1162722 YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		1162684 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		931213 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		1145680 LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		1145722 YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		1145708 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		931195 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		403182 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		563115 YBOX3_HUMAN (46-324): 2.21e-55: 186: 51.69		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		1116336 LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		1116641 YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		1116554 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		403342 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		931234 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		931308 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23
+	Hs
		1168899 LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		1174877 YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		1174855 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		1268171 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23