Protein: GLR
Glucagon receptor (GL-R)

Gene: GLR, GCGR
Organism: Homo sapiens
Interactions: 108
UniProt ID: P47871

Gene Ontology (top 5):
GO:0004967 - glucagon receptor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005886 - plasma membrane
GO:0006091 - generation of precursor metabolites and energy
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

867984

WDFY3
WD repeat and FYVE domain-containing protein 3

1

2

High-throughput

0.691

High

193688

TPSN
Tapasin

1

3

High-throughput

0.618

High

867995

DMXL2
DmX-like protein 2

1

3

High-throughput

0.618

High

226417

SNG2
Synaptogyrin-2

1

6

High-throughput

0.536

High

248568

FADS1
Acyl-CoA

1

2

High-throughput

0.536

High

256005

S19A2
Thiamine transporter 1

1

5

High-throughput

0.536

High

336532

PIGN
GPI ethanolamine phosphate transferase 1

1

9

High-throughput

0.536

High

349392

TSN15
Tetraspanin-15

1

15

High-throughput

0.536

High

565578

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

7

High-throughput

0.536

High

665548

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

2

High-throughput

0.536

High

852694

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

2

High-throughput

0.536

High

867949

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

High-throughput

0.536

High

867950

KNTC1
Kinetochore-associated protein 1

1

1

High-throughput

0.536

High

867952

AT12A
Potassium-transporting ATPase alpha chain 2

1

6

High-throughput

0.536

High

867953

CXCR4
C-X-C chemokine receptor type 4

1

6

High-throughput

0.536

High

867957

CLN3
Battenin

1

3

High-throughput

0.536

High

867958

ATM
Serine-protein kinase ATM

1

6

High-throughput

0.536

High

867959

MTX1
Metaxin-1

1

4

High-throughput

0.536

High

867960

MTR1L
Melatonin-related receptor

1

6

High-throughput

0.536

High

867963

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

2

High-throughput

0.536

High

867964

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

2

High-throughput

0.536

High

867969

TM164
Transmembrane protein 164

1

1

High-throughput

0.536

High

867971

RN213
E3 ubiquitin-protein ligase RNF213

1

1

High-throughput

0.536

High

867972

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

1

High-throughput

0.536

High

867973

ATLA3
Atlastin-3

1

3

High-throughput

0.536

High

867976

MBOA5
Lysophospholipid acyltransferase 5

1

3

High-throughput

0.536

High

867978

NIPA1
Magnesium transporter NIPA1

1

6

High-throughput

0.536

High

867979

DYM
Dymeclin

1

4

High-throughput

0.536

High

867985

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

1

5

High-throughput

0.536

High

867986

INT1
Integrator complex subunit 1

1

5

High-throughput

0.536

High

867991

ATLA2
Atlastin-2

1

3

High-throughput

0.536

High

867992

S35G2
Solute carrier family 35 member G2

1

12

High-throughput

0.536

High

867994

CIP2A
Protein CIP2A

1

3

High-throughput

0.536

High

868000

LMBR1
Limb region 1 protein homolog

1

1

High-throughput

0.536

High

868002

CDS1
Phosphatidate cytidylyltransferase 1

1

2

High-throughput

0.536

High

868003

GLMN
Glomulin

1

3

High-throughput

0.536

High

868007

COQ8B
Atypical kinase COQ8B, mitochondrial

1

5

High-throughput

0.536

High

868008

RB39B
Ras-related protein Rab-39B

1

1

High-throughput

0.536

High

868013

COG8
Conserved oligomeric Golgi complex subunit 8

1

3

High-throughput

0.536

High

868015

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

2

High-throughput

0.536

High

868019

PIGU
GPI-anchor transamidase component PIGU

1

1

High-throughput

0.536

High

868022

GPC5C
G-protein coupled receptor family C group 5 member C

1

6

High-throughput

0.536

High

868024

AIG1
Androgen-induced gene 1 protein

1

2

High-throughput

0.536

High

868031

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

3

High-throughput

0.536

High

333562

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.513

High

867955

NTCP7
Sodium/bile acid cotransporter 7

1

0

High-throughput

0.513

High

867970

TM268
Transmembrane protein 268

1

0

High-throughput

0.513

High

867974

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

867983

LIPB1
Liprin-beta-1

1

0

High-throughput

0.513

High

867996

ARH40
Rho guanine nucleotide exchange factor 40

1

0

High-throughput

0.513

High

867999

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

868006

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.513

High

868010

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.513

High

868012

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

0

High-throughput

0.513

High

137200

EXOC5
Exocyst complex component 5

1

1

High-throughput

0.489

High

173679

BTAF1
TATA-binding protein-associated factor 172

1

5

High-throughput

0.489

High

360262

COX1
Cytochrome c oxidase subunit 1

1

1

High-throughput

0.489

High

397587

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

1

High-throughput

0.489

High

397792

ATP8
ATP synthase F(0) complex subunit 8

1

1

High-throughput

0.489

High

630718

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.489

High

665077

COT2
COUP transcription factor 2

1

3

High-throughput

0.489

High

867954

REEP5
Receptor expression-enhancing protein 5

1

4

High-throughput

0.489

High

867962

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

1

High-throughput

0.489

High

867965

S2535
Solute carrier family 25 member 35

1

3

High-throughput

0.489

High

867966

TBB8
Tubulin beta-8 chain

1

3

High-throughput

0.489

High

867967

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

6

High-throughput

0.489

High

867968

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

3

High-throughput

0.489

High

867975

ACD10
Acyl-CoA dehydrogenase family member 10

1

3

High-throughput

0.489

High

867977

HACD2
Very-long-chain

1

3

High-throughput

0.489

High

867980

SETX
Probable helicase senataxin

1

2

High-throughput

0.489

High

867981

MAVS
Mitochondrial antiviral-signaling protein

1

2

High-throughput

0.489

High

867982

ADCK1
AarF domain-containing protein kinase 1

1

5

High-throughput

0.489

High

867987

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

2

High-throughput

0.489

High

867988

GUF1
Translation factor GUF1, mitochondrial

1

1

High-throughput

0.489

High

867989

CERS5
Ceramide synthase 5

1

10

High-throughput

0.489

High

867993

TBC15
TBC1 domain family member 15

1

12

High-throughput

0.489

High

867998

COG1
Conserved oligomeric Golgi complex subunit 1

1

1

High-throughput

0.489

High

868001

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

1

High-throughput

0.489

High

868004

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.489

High

868005

EVI5L
EVI5-like protein

1

7

High-throughput

0.489

High

868014

CP2S1
Cytochrome P450 2S1

1

4

High-throughput

0.489

High

868016

XPO4
Exportin-4

1

8

High-throughput

0.489

High

868020

SG196
Protein O-mannose kinase

1

3

High-throughput

0.489

High

868021

COG4
Conserved oligomeric Golgi complex subunit 4

1

1

High-throughput

0.489

High

868023

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

7

High-throughput

0.489

High

868025

ELOV2
Very long chain fatty acid elongase 2

1

6

High-throughput

0.489

High

868026

IPO11
Importin-11

1

13

High-throughput

0.489

High

868027

TPC1
Two pore channel protein 1

1

8

High-throughput

0.489

High

868030

TNPO3
Transportin-3

1

14

High-throughput

0.489

High

157078

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

867961

BMPR2
Bone morphogenetic protein receptor type-2

1

2

Small-scale

0.479

High

867997

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

1

Small-scale

0.479

High

642525

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.460

High

222813

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

340622

STABP
STAM-binding protein

1

0

Small-scale

0.458

High

867956

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

868018

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

867951

SC5A3
Sodium/myo-inositol cotransporter

1

2

High-throughput

0.445

High

506574

GPHRB
Golgi pH regulator B

1

9

High-throughput

0.437

High

85350

GPHRA
Golgi pH regulator A

1

9

High-throughput

0.407

High

167065

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.279

Low

187312

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.279

Low

867990

RDH13
Retinol dehydrogenase 13

1

0

High-throughput

0.279

Low

868009

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.279

Low

868011

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.279

Low

868028

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

0

High-throughput

0.279

Low

868029

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.279

Low

868017

P63
Tumor protein 63

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025