HitPredict

Interactor 1: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Interactor 2: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	11782456
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005925 - focal adhesion
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 476
+	Hs
		418964 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00
+	Hs
		1076422 Q5VU62_HUMAN (91-248): 4.79e-45: 150: 76.58		TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00
+	Hs
		451325 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		TES_HUMAN (141-457): 1.24e-56: 195: 19.09
+	Hs
		451318 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		110806 H7BYY1_HUMAN (1-248): 8.1e-49: 162: 77.82		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		419055 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		932058 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		434438 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Mm
		886037 TPM1_MOUSE (4-248): 1.11e-48: 163: 68.57		PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03
+	Mm
		886046 TPM2_MOUSE (4-248): 5.85e-42: 146: 69.39		PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03
+	Hs
		434422 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		PDLI5_HUMAN (249-334): 7.45e-09: 60: 20.93