Protein: UBP34
Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)

Gene: UBP34, USP34
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q70CQ2

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1257940

ERMAP
Erythroid membrane-associated protein

2

12

High-throughput

0.811

High

508176

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

20

Small-scale

0.806

High

876908

KC1A
Casein kinase I isoform alpha

5

4

High-throughput

0.725

High

1257906

EIF3M
Eukaryotic translation initiation factor 3 subunit M

3

2

High-throughput

0.667

High

1257933

ZN707
Zinc finger protein 707

3

4

High-throughput

0.667

High

69794

ZN785
Zinc finger protein 785

3

8

High-throughput

0.662

High

216472

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

5

High-throughput

0.628

High

1257909

ZN550
Zinc finger protein 550

2

6

High-throughput

0.628

High

1257932

ZN669
Zinc finger protein 669

2

6

High-throughput

0.628

High

1257935

ZN764
Zinc finger protein 764

2

6

High-throughput

0.628

High

1257961

ZN214
Zinc finger protein 214

2

4

High-throughput

0.628

High

1249794

BTNL9
Butyrophilin-like protein 9

1

15

High-throughput

0.618

High

1257922

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

872460

SOX2
Transcription factor SOX-2

2

10

Small-scale

0.611

High

640199

EPHA1
Ephrin type-A receptor 1

3

4

High-throughput

0.604

High

1103867

ZN211
Zinc finger protein 211

2

4

High-throughput

0.601

High

1102194

ATM
Serine-protein kinase ATM

2

7

Small-scale

0.584

High

1257956

ZRAN1
Ubiquitin thioesterase ZRANB1

2

9

High-throughput

0.584

High

1257916

SH2D3
SH2 domain-containing protein 3C

2

15

High-throughput

0.571

High

1257913

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

2

4

High-throughput

0.549

High

1115752

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

10

High-throughput

0.541

High

574054

HXB1
Homeobox protein Hox-B1

1

6

High-throughput

0.536

High

578672

GLNA
Glutamine synthetase

1

1

High-throughput

0.536

High

638599

ZNF10
Zinc finger protein 10

1

3

High-throughput

0.536

High

649346

H1T
Histone H1t

1

10

High-throughput

0.536

High

679361

DNJB2
DnaJ homolog subfamily B member 2

1

4

High-throughput

0.536

High

1041768

PPARD
Peroxisome proliferator-activated receptor delta

1

9

High-throughput

0.536

High

1128643

ZN460
Zinc finger protein 460

1

3

High-throughput

0.536

High

1187841

FX4L6
Forkhead box protein D4-like 6

1

7

High-throughput

0.536

High

1257915

Z354C
Zinc finger protein 354C

1

3

High-throughput

0.536

High

1257917

TSYL6
Testis-specific Y-encoded-like protein 6

1

9

High-throughput

0.536

High

1257924

DNJB8
DnaJ homolog subfamily B member 8

1

8

High-throughput

0.536

High

1257925

ZN418
Zinc finger protein 418

1

4

High-throughput

0.536

High

1257928

FGF14
Fibroblast growth factor 14

1

4

High-throughput

0.536

High

1257930

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

1257937

ZN514
Zinc finger protein 514

1

5

High-throughput

0.536

High

1257950

AGO4
Protein argonaute-4

1

1

High-throughput

0.536

High

1257958

HSPB8
Heat shock protein beta-8

1

4

High-throughput

0.536

High

1257964

TRI35
E3 ubiquitin-protein ligase TRIM35

1

14

High-throughput

0.536

High

1257966

GAB2
GRB2-associated-binding protein 2

1

10

High-throughput

0.536

High

351489

FTCD
Formimidoyltransferase-cyclodeaminase

1

0

High-throughput

0.518

High

1257914

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.514

High

884132

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

1064577

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1081794

MESP2
Mesoderm posterior protein 2

1

0

High-throughput

0.513

High

1163925

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

1207223

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1257942

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1257949

B2L12
Bcl-2-like protein 12

1

0

High-throughput

0.513

High

416962

CY24B
NADPH oxidase 2

1

2

High-throughput

0.489

High

505101

BNIP5
Protein BNIP5

1

1

High-throughput

0.489

High

618394

TSN8
Tetraspanin-8

1

1

High-throughput

0.489

High

1006265

CTG1B
Cancer/testis antigen 1

1

1

High-throughput

0.489

High

1177006

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1211627

SPT46
Spermatogenesis-associated protein 46

1

1

High-throughput

0.489

High

1257936

LOXL4
Lysyl oxidase homolog 4

1

5

High-throughput

0.489

High

143072

NFIB
Nuclear factor 1 B-type

1

7

High-throughput

0.479

High

246702

KDM1A
Lysine-specific histone demethylase 1A

1

9

High-throughput

0.479

High

260105

BRD4
Bromodomain-containing protein 4

1

17

High-throughput

0.479

High

315713

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

342229

BRD1
Bromodomain-containing protein 1

1

9

High-throughput

0.479

High

363467

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

372379

MYC
Myc proto-oncogene protein

1

12

Small-scale

0.479

High

414080

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

474084

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.479

High

520154

ANDR
Androgen receptor

1

15

High-throughput

0.479

High

588989

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

691781

MK03
Mitogen-activated protein kinase 3

1

3

High-throughput

0.479

High

695776

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

703631

MK01
Mitogen-activated protein kinase 1

1

3

High-throughput

0.479

High

714215

PML
Protein PML

1

16

High-throughput

0.479

High

790060

ZEB1
Zinc finger E-box-binding homeobox 1

1

10

Small-scale

0.479

High

821421

TCPZ
T-complex protein 1 subunit zeta

1

6

High-throughput

0.479

High

1004745

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.479

High

1023256

RBM3
RNA-binding protein 3

1

8

Small-scale

0.479

High

1033707

PO5F1
POU domain, class 5, transcription factor 1

1

4

High-throughput

0.479

High

1087823

NFIA
Nuclear factor 1 A-type

1

7

High-throughput

0.479

High

1088884

TP53B
TP53-binding protein 1

1

5

High-throughput

0.479

High

1096728

RFA4
Replication protein A 30 kDa subunit

1

8

High-throughput

0.479

High

1113492

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1114908

CUL4A
Cullin-4A

1

11

High-throughput

0.479

High

1133488

NFIX
Nuclear factor 1 X-type

1

10

High-throughput

0.479

High

1135717

HAPR1
HUWE1-associated protein modifying stress responses 1

1

2

High-throughput

0.479

High

1257905

DPPA4
Developmental pluripotency-associated protein 4

1

1

High-throughput

0.479

High

1257910

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1257911

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

15

High-throughput

0.479

High

1257923

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

1257934

SPDLY
Protein Spindly

1

15

High-throughput

0.479

High

1257941

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

1257943

DUS15
Dual specificity protein phosphatase 15

1

6

High-throughput

0.479

High

1257945

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

1257947

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1257948

NANOG
Homeobox protein NANOG

1

5

High-throughput

0.479

High

1257951

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

13

High-throughput

0.479

High

1257954

ARL8B
ADP-ribosylation factor-like protein 8B

1

3

High-throughput

0.479

High

1257957

HERC5
E3 ISG15--protein ligase HERC5

1

14

Small-scale

0.479

High

1257959

RCOR1
REST corepressor 1

1

2

High-throughput

0.479

High

1257960

AMFR
E3 ubiquitin-protein ligase AMFR

1

5

Small-scale

0.479

High

1257963

FZR1
Fizzy-related protein homolog

1

15

High-throughput

0.479

High

869761

MTR1A
Melatonin receptor type 1A

1

4

High-throughput

0.464

High

880934

MTR1B
Melatonin receptor type 1B

1

3

High-throughput

0.464

High

1257952

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

76475

ZN736
Zinc finger protein 736

1

2

High-throughput

0.445

High

171488

S27A2
Long-chain fatty acid transport protein 2

1

4

High-throughput

0.445

High

181132

AXIN1
Axin-1

1

4

Small-scale

0.445

High

600101

ZNF20
Zinc finger protein 20

1

3

High-throughput

0.445

High

1159260

ZNF74
Zinc finger protein 74

1

4

High-throughput

0.445

High

1257907

ZN765
Zinc finger protein 765

1

2

High-throughput

0.445

High

1257908

ZN627
Zinc finger protein 627

1

6

High-throughput

0.445

High

1257944

E41L1
Band 4.1-like protein 1

1

7

High-throughput

0.445

High

1257953

ZFP57
Zinc finger protein 57 homolog

1

6

High-throughput

0.445

High

218365

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

768494

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

886288

ARL4D
ADP-ribosylation factor-like protein 4D

1

5

High-throughput

0.437

High

1034487

TAGL
Transgelin

1

7

Small-scale

0.437

High

1254351

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1257912

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

7

High-throughput

0.437

High

1257926

DCAF4
DDB1- and CUL4-associated factor 4

1

4

High-throughput

0.437

High

1257929

ARL11
ADP-ribosylation factor-like protein 11

1

4

High-throughput

0.437

High

1257931

PF21A
PHD finger protein 21A

1

6

High-throughput

0.437

High

166330

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

4

High-throughput

0.407

High

638457

FPR1
fMet-Leu-Phe receptor

1

6

High-throughput

0.407

High

1101548

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.407

High

1219499

ANR22
Ankyrin repeat domain-containing protein 22

1

6

High-throughput

0.407

High

1253620

PKHG7
Pleckstrin homology domain-containing family G member 7

1

4

High-throughput

0.407

High

1257927

LPAR1
Lysophosphatidic acid receptor 1

1

6

High-throughput

0.407

High

1257962

FZD10
Frizzled-10

1

3

High-throughput

0.407

High

1257965

XCT
Cystine/glutamate transporter

1

2

High-throughput

0.407

High

1248551

LYPD4
Ly6/PLAUR domain-containing protein 4

2

0

High-throughput

0.328

High

1257955

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.313

High

261515

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

892975

ENTP1
Ectonucleoside triphosphate diphosphohydrolase 1

1

0

High-throughput

0.279

Low

1234751

CK071
Uncharacterized protein C11orf71

1

0

High-throughput

0.279

Low

1257919

CO053
Putative uncharacterized protein encoded by LINC02694

1

0

High-throughput

0.279

Low

1257921

FA83F
Protein FAM83F

1

0

High-throughput

0.279

Low

1257946

RPP21
Ribonuclease P protein subunit p21

1

0

High-throughput

0.279

Low

1257967

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.279

Low

1257938

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

50598

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

1036611

ZNF45
Zinc finger protein 45

1

0

High-throughput

0.232

Low

1257918

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low

1257920

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.232

Low

1257939

PTHD1
Patched domain-containing protein 1

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025