HitPredict

Interactor 1: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Interactor 2: IQCB1 (Q15051)
IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)
Gene: IQCB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21565611
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015630 - microtubule cytoskeleton GO:0045171 - intercellular bridge GO:0070062 - extracellular exosome GO:0072686 - mitotic spindle
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 598
+	Mm
		934056 TBB4B_MOUSE (1-427): 0: 711: 100.00		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Mm
		958400 TBB5_MOUSE (1-429): 0: 711: 98.37		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Hs
		1037236 TBB3_HUMAN (1-443): 0: 714: 93.23		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		428219 TBB5_HUMAN (1-429): 0: 711: 98.37		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		1046470 TBB2A_HUMAN (1-430): 0: 707: 97.67		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		1065992 TBB6_HUMAN (1-432): 0: 706: 92.36		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Mm
		1206955 TBB6_MOUSE (1-429): 0: 701: 93.01		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Hs
		1065930 TBB8_HUMAN (1-427): 0: 704: 91.10		IQCB1_HUMAN (1-598): 0: 1065: 100.00