HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 25281560, 29506131, 31018966, 32609811, 34079125, 33961781, 34766381, 36089195, 30639225, 32144273, 30392931, 32428527, 33097091, 22096602, 36458887, 22064703, 17967883
Identification Methods proximity labelling technology, unspecified method, affinity chromatography technology, enzymatic study, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Histone~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0040029 - epigenetic regulation of gene expression
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 136
Hs

1 793
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Last updated: 15 Jul 2024