Protein: TB22A
TBC1 domain family member 22A

Gene: TB22A, TBC1D22A
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q8WUA7

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005794 - Golgi apparatus
GO:0042803 - protein homodimerization activity
GO:0071889 - 14-3-3 protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1356482

TB22B
TBC1 domain family member 22B

2

7

High-throughput

0.811

High

1356480

GCP60
Golgi resident protein GCP60

4

1

Small-scale

0.701

High

1356472

NECT2
Nectin-2

3

2

High-throughput

0.667

High

901428

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.618

High

298941

DNJB5
DnaJ homolog subfamily B member 5

3

4

High-throughput

0.609

High

932106

EPHA4
Ephrin type-A receptor 4

3

10

High-throughput

0.609

High

1153475

EFNB3
Ephrin-B3

3

2

High-throughput

0.609

High

1315584

MICU2
Calcium uptake protein 2, mitochondrial

3

8

High-throughput

0.609

High

1356475

KIRR1
Kin of IRRE-like protein 1

3

1

High-throughput

0.609

High

1356477

MICU1
Calcium uptake protein 1, mitochondrial

3

8

High-throughput

0.609

High

1356483

DNJB4
DnaJ homolog subfamily B member 4

3

4

High-throughput

0.609

High

1356486

EXOG
Nuclease EXOG, mitochondrial

3

1

High-throughput

0.609

High

242397

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

261641

CATL2
Cathepsin L2

1

3

High-throughput

0.489

High

486595

TACD2
Tumor-associated calcium signal transducer 2

1

5

High-throughput

0.489

High

730090

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.489

High

218533

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.479

High

1356487

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

2

High-throughput

0.479

High

231743

PEX1
Peroxisomal ATPase PEX1

1

5

High-throughput

0.470

High

1253778

QSOX2
Sulfhydryl oxidase 2

1

0

High-throughput

0.458

High

628367

CD33
Myeloid cell surface antigen CD33

1

2

High-throughput

0.445

High

761463

HS71L
Heat shock 70 kDa protein 1-like

1

1

High-throughput

0.437

High

1356479

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

2

High-throughput

0.437

High

1356481

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

2

High-throughput

0.437

High

1356484

XPO7
Exportin-7

1

9

High-throughput

0.437

High

1356478

DPY30
Protein dpy-30 homolog

1

0

Small-scale

0.426

High

262276

SCN2B
Sodium channel regulatory subunit beta-2

1

2

High-throughput

0.407

High

281766

VP26A
Vacuolar protein sorting-associated protein 26A

1

2

Small-scale

0.407

High

589250

RFA2
Replication protein A 32 kDa subunit

1

6

Small-scale

0.407

High

640237

EPHA1
Ephrin type-A receptor 1

1

8

High-throughput

0.407

High

696035

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

Small-scale

0.407

High

768734

RFA3
Replication protein A 14 kDa subunit

1

5

Small-scale

0.407

High

1258521

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.407

High

1279065

RIC3
Protein RIC-3

1

1

High-throughput

0.407

High

1340491

DNJB8
DnaJ homolog subfamily B member 8

1

4

High-throughput

0.407

High

1355996

CLC4C
C-type lectin domain family 4 member C

1

3

High-throughput

0.407

High

1356474

AURKB
Aurora kinase B

1

5

High-throughput

0.407

High

1356476

VPS35
Vacuolar protein sorting-associated protein 35

1

2

Small-scale

0.407

High

249495

ACSL4
Long-chain-fatty-acid--CoA ligase 4

3

0

High-throughput

0.347

High

649898

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

3

0

High-throughput

0.347

High

1270313

SPT6H
Transcription elongation factor SPT6

3

0

High-throughput

0.347

High

1356473

FWCH2
FLYWCH family member 2

3

0

High-throughput

0.347

High

1329635

EFNMT
eEF1A lysine and N-terminal methyltransferase

2

0

High-throughput

0.318

High

1349965

CERK1
Ceramide kinase

1

0

High-throughput

0.279

Low

1349797

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.269

Low

301593

WFS1
Wolframin

1

0

High-throughput

0.268

Low

389860

TTHY
Transthyretin

1

0

High-throughput

0.268

Low

890991

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.268

Low

1271652

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

Small-scale

0.232

Low

1356485

PA2G4
Proliferation-associated protein 2G4

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025