HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: PHF8 (Q9UPP1)
Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8)
Gene: PHF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.755

Property	Details
Experiments	36089195, 20208542, 20421419, 20346720, 20622853, 20548336, 20531378, 26496610
Identification Methods	proximity labelling technology, pull down, affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1060
+	Hs
		1086352 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PHF8_HUMAN (1-1060): 0: 1403: 100.00
+	Hs
		952701 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PHF8_HUMAN (1-1060): 0: 1403: 100.00
+	Hs
		256400 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256412 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256401 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256416 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		935393 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		1086360 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		952712 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		935008 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Hs
		952482 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Hs
		1174601 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Hs
		934702 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		1017307 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Mm
		93660 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		E9Q6A7_MOUSE (30-153): 4.99e-29: 128: 22.40
+	Hs
		952300 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		1017316 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		935185 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43
+	Hs
		1086300 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43
+	Hs
		952594 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43