Protein: SSH3
Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)

Gene: SSH3
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q8TE77

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158474

RFXK
DNA-binding protein RFXANK

1

9

High-throughput

0.691

High

1110512

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

High-throughput

0.691

High

960499

PSME3
Proteasome activator complex subunit 3

3

4

High-throughput

0.667

High

1153202

HERC1
Probable E3 ubiquitin-protein ligase HERC1

3

2

High-throughput

0.667

High

537580

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.628

High

833760

KDM5C
Lysine-specific demethylase 5C

2

1

High-throughput

0.628

High

1352189

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

2

1

High-throughput

0.628

High

1352193

ANGE1
Protein angel homolog 1

2

1

High-throughput

0.628

High

1352177

SSH3
Protein phosphatase Slingshot homolog 3

1

19

High-throughput

0.618

High

222159

NCK2
Cytoplasmic protein NCK2

2

13

High-throughput

0.606

High

946511

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1352192

MKS1
Tectonic-like complex member MKS1

2

0

High-throughput

0.602

High

1352179

K0232
Uncharacterized protein KIAA0232

2

1

High-throughput

0.574

High

1147974

SF3B3
Splicing factor 3B subunit 3

1

1

High-throughput

0.536

High

1339820

PJA1
E3 ubiquitin-protein ligase Praja-1

1

2

High-throughput

0.536

High

1352181

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1352187

NADAP
Kanadaptin

1

1

High-throughput

0.536

High

1352194

TRI35
E3 ubiquitin-protein ligase TRIM35

1

3

High-throughput

0.536

High

1352182

OTUB1
Ubiquitin thioesterase OTUB1

2

4

High-throughput

0.521

High

1177039

INF2
Inverted formin-2

1

0

High-throughput

0.513

High

1352195

ZN330
Zinc finger protein 330

1

0

High-throughput

0.513

High

422696

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

1122754

DPOA2
DNA polymerase alpha subunit B

1

1

High-throughput

0.489

High

1231271

BLT3A
Bridge-like lipid transfer protein family member 3A

1

1

High-throughput

0.489

High

176691

PUR4
Phosphoribosylformylglycinamidine synthase

1

1

High-throughput

0.479

High

556237

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

643526

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

731494

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

922267

LIMK1
LIM domain kinase 1

1

17

Small-scale

0.479

High

1045556

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

1121473

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.479

High

1324021

RHG24
Rho GTPase-activating protein 24

1

2

High-throughput

0.479

High

1352184

CK5P2
CDK5 regulatory subunit-associated protein 2

1

13

High-throughput

0.479

High

1352186

AFG2B
ATPase family gene 2 protein homolog B

1

4

High-throughput

0.479

High

1352190

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

3

High-throughput

0.479

High

229765

CALU
Calumenin

1

6

High-throughput

0.437

High

945053

RAB25
Ras-related protein Rab-25

1

3

High-throughput

0.437

High

996503

ACTS
Actin, alpha skeletal muscle

1

9

Small-scale

0.437

High

1128789

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.437

High

1228936

CRBG3
Very large A-kinase anchor protein

1

1

High-throughput

0.437

High

1352178

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

1

High-throughput

0.437

High

1352183

FMC1
Protein FMC1 homolog

2

0

High-throughput

0.328

High

662794

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1352180

F162A
Protein FAM162A

1

0

High-throughput

0.279

Low

1352185

SORT
Sortilin

1

0

High-throughput

0.279

Low

1352191

TM248
Transmembrane protein 248

1

0

High-throughput

0.279

Low

1352188

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025