HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007267 - cell-cell signaling
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1824 Hs			1 346
+	Hs
		914391 AFAD_HUMAN (1-1824): 0: 1266: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		1022856 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		1022936 RADIL_HUMAN (830-1106): 5.37e-28: 125: 17.36		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		914417 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		1022843 PTN13_HUMAN (978-1091): 1.19e-17: 92.2: 35.83		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Mm
		914175 PTN13_MOUSE (1003-1147): 1.9e-16: 88.3: 27.49		EFNB1_MOUSE (1-346): 0: 523: 95.67
+	Hs
		914469 RADIL_HUMAN (830-1106): 5.37e-28: 125: 17.36		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		914261 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		EFNA4_HUMAN (13-211): 5.62e-53: 175: 23.42