HitPredict

Interactor 1: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Interactor 2: TF2L1 (Q3UNW5)
Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1)
Gene: Tfcp2l1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20362541
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 488 Mm			1 479
+	Hs
		1016829 HDAC2_HUMAN (1-488): 0: 707: 99.39		TFCP2_HUMAN (16-476): 0: 763: 72.07
+	Mm
		140265 HDAC1_MOUSE (1-446): 0: 647: 89.46		TF2L1_MOUSE (1-479): 0: 809: 100.00
+	Hs
		1016757 HDAC1_HUMAN (1-446): 0: 643: 89.24		TFCP2_HUMAN (16-476): 0: 763: 72.07
+	Mm
		1157710 HDAC4_MOUSE (1-377): 7.49e-132: 409: 23.89		UBIP1_MOUSE (16-476): 0: 708: 61.89